Advanced breast cancer (metastatic)
Gastric or gastro-oesophageal junction cancer (advanced)
Renal-cell carcinoma (advanced)
Urothelial carcinoma (advanced)
Atrioventricular block or sick sinus syndrome
Heart failure with preserved LVEF
Left ventricular dysfunction after myocardial infarction
Patients at high risk for cardiovascular events
Patients with implantable cardioverter defibrillators
Percutaneous coronary intervention
Progression of atherosclerosis
Ventricular tachycardia in patients with structural heart disease