heart failure with preserved LVEF

systematic review meta-analysis network meta-analysis

Select All mechanism All type of patient       angiotensin receptor blockerangiotensin receptor neprilysin inhibitorAngiotensin-Converting Enzyme Inhibitorsmineralocorticoid receptor antagonists perindoprilirbesartancandesartan vs placebo or controlvs placebo or no treatment      

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Group by Group by... nothing pathology treatment patient comparator classe classe comparator mechanism clinical condition MA  in first nothing pathology treatment patient comparator classe classe comparator mechanism clinical condition  in second nothing pathology treatment patient comparator classe classe comparator mechanism clinical condition  in third	Description Synopsis Comparison Treatments Patients Characteristics Method Risk of bias References None Tools Indexation					Results Global trial result Main results All results All result tag NCT results	hospitalisation for heart failure (3)All cause death (2)Cardiovascular death or hospital admission for CHF (2)Cardiovascular death (2)Hospitalization for any reason (1)death or cardiovascular hospitalization (1)Death from any cause or hospitalization for any reason (1)Long term death (1) Options Numeric bar chart forest plot medians
Trial	Studied trt	Control trt	patients	tags	ROB	Trial result	hospitalisation for heart failure	All cause death
All mechanism
not classified
Edlemann, 2013						-
TOPCAT, 2014      NCT	spironolactone	placebo			Low risk of bias	-
PARAMOUNT, 2012        NCT	LCZ696	valsartan			Low risk of bias	-
candesartan
CHARM preserved, 2003	candesartan	placebo			Low risk of bias	-
irbesartan
I-PRESERVE (McMurray), 2008      NCT	ibesartan	placebo			Low risk of bias	negative
perindopril
PEP CHF, 2006	perindopril	placebo			Low risk of bias	negative