impaired fasting glucose

systematic review meta-analysis network meta-analysis

Select prevention All type of patient       alpha-glucosidase inhibitorangiotensin receptor blockerangiotensin-converting enzyme inhibitorsantidiabetic drugsglitazonesinsulinlifestyle modificationn-3 fatty acid supplement ramiprilvalsartanglarginemetforminnategliniderosiglitazonevoglibose vs placebo or control      

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Group by Group by... nothing pathology treatment patient comparator classe classe comparator mechanism clinical condition MA  in first nothing pathology treatment patient comparator classe classe comparator mechanism clinical condition  in second nothing pathology treatment patient comparator classe classe comparator mechanism clinical condition  in third	Description Synopsis Comparison Treatments Patients Characteristics Method Risk of bias References None Tools Indexation					Results Global trial result Main results All results All result tag NCT results	Diabetes (8)cardiovascular events (4)All cause death (4)Cardiovascular death (4)normoglycemia (3)myocardial infarction (fatal and non fatal) (2)stroke (fatal and non fatal) (2)hospitalisation for heart failure (2)cardiovascular death, MI, stroke (1) Options Numeric bar chart forest plot medians
Trial	Studied trt	Control trt	patients	tags	ROB	Trial result	Diabetes	cardiovascular events
prevention
not classified
US-DDP (lifestyle) (Knowler), 2002	lifestyle modification	control			Risk of bias	-
STOP-NIDDM (Chiasson), 2002	error	placebo			Low risk of bias	negative
GRACE - ORIGIN (n-3 fatty acid)	n-3 fatty acid supplement	placebo			Low risk of bias	-
glargine
GRACE - ORIGIN (glargine), 2012	insulin glargine	placebo			Risk of bias	-
metformin
US-DPP (metformin) (Knowler), 2002	metformin	placebo			Low risk of bias	negative
CANOE, 2010      NCT	rosiglitazone and metformin	placebo			Low risk of bias	suggesting
nateglinide
NAVIGATOR nateglinide, 2010    NCT	nateglinide	placebo			Low risk of bias	negative
ramipril
DREAM ramipril, 2006        NCT	ramipril	placebo			Low risk of bias	negative
rosiglitazone
DREAM rosiglitazone, 2006      NCT	rosiglitazone	placebo			Low risk of bias	suggesting
valsartan
NAVIGATOR valsartan, 2010        NCT	valsartan	placebo			Low risk of bias	suggesting
voglibose
Voglibose Ph-3, 2009	voglibose	placebo			Low risk of bias	suggesting