Ramipril angiotensin-Converting Enzyme Inhibitors
systematic review meta-analysis network meta-analysis
 

Zabien - Tritace - Acovil - Carasel - Vesdil - Ramace - Delix - Altace - Triatec      

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Trial Studied trt Control trt patientstagsROB Trial resultAll cause deathstroke (fatal and non fatal)

acute myocardial infarction  

AIRE, 1993   ramiprilplaceboLow risk of bias -
Wagner, 2002   ramiprilplaceboLow risk of bias -

diabetes type 2  

DREAM ramipril, 2006        NCTramiprilplaceboLow risk of bias negative -2%
DIABHYCAR, 2004     ramiprilplaceboLow risk of bias negative 4%3%
DREAM, 2008       ramiprilplacebonegative-2%-50%

diabetic kidney disease  

DIABHYCAR, 2004     ramiprilplaceboLow risk of bias negative 4%3%

heart failure  

Swedberg, 1991   ramiprilcontrolnegative
Maass-a, 1991   ramiprilplacebonegative
Gordon, 1991     ramiprilplaceboLow risk of bias suggesting
Maass-b, 1991   ramiprilplaceboLow risk of bias negative
Maass-c, 1991     ramiprilplaceboLow risk of bias negative
Lemarie, 1992     ramiprilplaceboLow risk of bias negative
AIRE, 1993   ramiprilplaceboLow risk of bias -
Gundersen, 1994     ramiprilplaceboLow risk of bias -

hypertension  

Li et al, 2003     ramiprilusual carenegative0%
AASK (ramipril vs amlodipine), 2002     ramiprilamlodipineLow risk of bias negative11%
AASK (ramipril vs metoprolol), 2002     ramiprilmetoprololLow risk of bias negative-23%
ONTARGET/Tel+Ram, 2008     Telmisartan + ramiprilRamiprilLow risk of bias negative6%-7%

impaired fasting glucose  

DREAM ramipril, 2006        NCTramiprilplaceboLow risk of bias negative -2%

miscellaneous  

ONTARGET (association vs ramipril), 2008    NCTtelmisartan + ramiprilramiprilLow risk of bias negative 6%-7%
ONTARGET (association vs telmisartan), 2008    NCTtelmisartan + ramipriltelmisartanLow risk of bias suggesting 8%2%

patients at high risk for cardiovascular events  

HOPE, 2000     ramiprilplaceboLow risk of bias suggesting -15%-31%
ONTARGET (association vs ramipril), 2008    NCTtelmisartan + ramiprilramiprilLow risk of bias negative 6%-7%
ONTARGET (association vs telmisartan), 2008    NCTtelmisartan + ramipriltelmisartanLow risk of bias suggesting 8%2%



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