new version V2017

Ticlopidine antiplatelets drug
Description Results

Ticlid - 5332C - 53 32C - 53-32C - Ticlodone - Ticlodix - Ticlopidine Hydrochloride - Ticlopidine      

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TrialStudied treatmentControl treatmentpatientsROBResultNCT

acute coronary syndrome

Florida UAticlopidineplaceboNegative
Knudsen-A, 1985ticlopidinecontrolNegative
STAI, 1990ticlopidinecontrolSuggesting

acute myocardial infarction

Knudsen-A, 1985ticlopidinecontrolNegative

CABG surgery

Zurich, 1982ticlopidinecontrol -
Romeo, 1983ticlopidinecontrol -
Knudsen-B, 1983ticlopidinecontrol -
Liège-I, 1984ticlopidineplaceboNegative
Liège-II, 1987ticlopidineplaceboNegative
Kohn, 1990ticlopidinecontrol -

cardiovascular prevention

Birmingham-A, 1979ticlopidineplaceboNegative
Hurlow, 1980ticlopidineplacebo -
Krause, 1980ticlopidineplacebo -
Katsumara, 1982ticlopidineplacebo -
Aukland, 1982ticlopidineplacebo -
London diabetes, 1983ticlopidineplaceboNegative
Stiegler, 1984ticlopidineplacebo -
Nyberg, 1984ticlopidineplacebo Low risk of bias Negative
TIMAD, 1984ticlopidineplaceboNegative
Berglund, 1985ticlopidineplacebo Exploratory Negative
Ellis, 1986ticlopidineplacebo -
Cloarec, 1986ticlopidineplacebo -
Arcan, 1988ticlopidineplacebo -
Balsano, 1989ticlopidineplacebo -
STIMS, 1990ticlopidineplacebo -
BTRS, 1992ticlopidineplaceboNegative
EMATAP, 1993ticlopidineplacebo -

coronary artery disease

Berglund, 1985ticlopidineplacebo Exploratory Negative

diabetes type 2

Birmingham-A, 1979ticlopidineplaceboNegative
London diabetes, 1983ticlopidineplaceboNegative
TIMAD, 1984ticlopidineplaceboNegative
Nyberg, 1984ticlopidineplacebo Low risk of bias Negative
BTRS, 1992ticlopidineplaceboNegative

percutaneous coronary intervention

TACT, 1990ticlopidineplaceboNegative
White (ticlopidine), 1991ticlopidineplacebo -
Hall, 1996ticlopidine + aspirinaspirinNegative
ISAR, 1996ticlopidine + aspirincoumadin + aspirinSuggesting
STARS (vs aspirin), 1998ticlopidine + aspirinaspirinSuggesting
MATTIS, 1998ticlopidine + aspirincoumadin + aspirinNegative
FANTASTIC, 1998ticlopidine + aspirincoumadin + aspirinNegative
STARS (vs coumadin+asp), 1998ticlopidine + aspirincoumadin + aspirinSuggesting
Foussas, 2000ticlopidine + aspirincoumadin + aspirinSuggesting

peripheral vascular diseases

Krause, 1980ticlopidineplacebo -
Hurlow, 1980ticlopidineplacebo -
Katsumara, 1982ticlopidineplacebo -
Aukland, 1982ticlopidineplacebo -
Stiegler, 1984ticlopidineplacebo -
Ellis, 1986ticlopidineplacebo -
Cloarec, 1986ticlopidineplacebo -
Arcan, 1988ticlopidineplacebo -
Balsano, 1989ticlopidineplacebo -
STIMS, 1990ticlopidineplacebo -
EMATAP, 1993ticlopidineplacebo -
Becquemin, 1997ticlopidinecontrôle -

stable angina

Berglund, 1985ticlopidineplacebo Exploratory Negative

stent

Hall, 1996ticlopidine + aspirinaspirinNegative
ISAR, 1996ticlopidine + aspirincoumadin + aspirinSuggesting
STARS (vs aspirin), 1998ticlopidine + aspirinaspirinSuggesting
MATTIS, 1998ticlopidine + aspirincoumadin + aspirinNegative
FANTASTIC, 1998ticlopidine + aspirincoumadin + aspirinNegative
STARS (vs coumadin+asp), 1998ticlopidine + aspirincoumadin + aspirinSuggesting
Foussas, 2000ticlopidine + aspirincoumadin + aspirinSuggesting

thrombosis prevention

Walker, 1974ticlopidineplacebo Exploratory -
Lasierra, 1982ticlopidineplacebo Exploratory -
McKenna-II, 1983Ticlopidineplacebo Exploratory Negative
McKenna-II , 1983ticlopidineplaceboNegative
Lyon-IITiclopidineplacebo Exploratory Negative
GardeckiTiclopidineplacebo Exploratory Negative



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