new version V2017

Dipyridamol antiplatelets drug
Description Results

dipyridamol monoacetate - dipyridamole monoacetate      

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TrialStudied treatmentControl treatmentpatientsROBResultNCT

acute coronary syndrome

Prandoni, 1991aspirin + dipyridamolplaceboNegative

CABG surgery

Pantely, 1979aspirin + dipyridamolcontrolNegative
Des Moines, 1980aspirin + dipyridamolcontrol -
Mayo-A, 1984aspirin + dipyridamolplaceboNegative
Wadsworth, 1985aspirin + dipyridamolplaceboNegative
Brooks, 1985aspirin + dipyridamolplaceboNegative
Leeds-B, 1985aspirin + dipyridamolplacebo -
Czech, 1986aspirin + dipyridamolcontrol -
Brussels, 1987aspirin + dipyridamolcontrolNegative
Toronto dipyridamole, 1987dipyridamolcontrol -
Thaulow, 1987aspirin + dipyridamolplacebo -
Basel, 1989aspirin + dipyridamolplaceboNegative
GESIC (aspirin+dipyridamol), 1990aspirin + dipyridamolplaceboNegative
Ekestrom, 1990dipyridamolplacebo -

cardiovascular prevention

Foulds, 1960dipyridamolplacebo Exploratory -
Dewar, 1961dipyridamolplacebo Exploratory -
Zion, 1961dipyridamolplacebo Exploratory -
Kinsella, 1962dipyridamolplacebo Exploratory -
Neumann, 1964dipyridamolplacebo Exploratory -
Leiberman, 1964dipyridamolplacebo Exploratory -
Wirecki, 1967dipyridamolcontrol Exploratory Negative
Atlanta (Sbar), 1967dipyridamolcontrol Exploratory Negative
Becker, 1967dipyridamolcontrol Exploratory Negative
Igloe, 1970dipyridamolplacebo Exploratory -
PARIS, 1980dipyridamol + aspirinaspirinNegative
PARIS, 1980dipyridamol + aspirinplaceboNegative
Schoop (2), 1983aspirin + dipyridamolplacebo -
Hess (2), 1985aspirin + dipyridamolplacebo -
PARIS-II, 1986dipyridamol + aspirinplaceboNegative
VA study, 1986aspirin + dipyridamolplacebo -

coronary artery disease

Foulds, 1960dipyridamolplacebo Exploratory -
Zion, 1961dipyridamolplacebo Exploratory -
Dewar, 1961dipyridamolplacebo Exploratory -
Kinsella, 1962dipyridamolplacebo Exploratory -
Leiberman, 1964dipyridamolplacebo Exploratory -
Neumann, 1964dipyridamolplacebo Exploratory -
Wirecki, 1967dipyridamolcontrol Exploratory Negative
Becker, 1967dipyridamolcontrol Exploratory Negative
Atlanta (Sbar), 1967dipyridamolcontrol Exploratory Negative
Igloe, 1970dipyridamolplacebo Exploratory -
PARIS, 1980dipyridamol + aspirinaspirinNegative
PARIS, 1980dipyridamol + aspirinplaceboNegative
PARIS-II, 1986dipyridamol + aspirinplaceboNegative

percutaneous coronary intervention

Schwartz (Toronto), 1988aspirin + dipyridamolplaceboSuggesting
Mayo-PTCA, 1989aspirin + dipyridamolplaceboNegative
Nye (Dunedin), 1990aspirin + dipyridamolplaceboNegative
White (aspirin+dipiridamol), 1991aspirin + dipyridamolplaceboNegative

peripheral vascular diseases

Schoop (2), 1983aspirin + dipyridamolplacebo -
Hess (2), 1985aspirin + dipyridamolplacebo -
VA study, 1986aspirin + dipyridamolplacebo -

post myocardial infarction

PARIS, 1980dipyridamol + aspirinaspirinNegative
PARIS, 1980dipyridamol + aspirinplaceboNegative
PARIS-II, 1986dipyridamol + aspirinplaceboNegative

stable angina

Foulds, 1960dipyridamolplacebo Exploratory -
Zion, 1961dipyridamolplacebo Exploratory -
Dewar, 1961dipyridamolplacebo Exploratory -
Kinsella, 1962dipyridamolplacebo Exploratory -
Leiberman, 1964dipyridamolplacebo Exploratory -
Neumann, 1964dipyridamolplacebo Exploratory -
Wirecki, 1967dipyridamolcontrol Exploratory Negative
Atlanta (Sbar), 1967dipyridamolcontrol Exploratory Negative
Becker, 1967dipyridamolcontrol Exploratory Negative
Igloe, 1970dipyridamolplacebo Exploratory -

thrombosis prevention

Parodi II, 1973dipyridamol + aspirincontrol Risk of bias -
Parodi I, 1973dipyridamol + aspirincontrol Exploratory Suggesting
Australian I, 1975dipyridamol + aspirincontrol Risk of bias -
Lyon-I, 1975aspirin + dipyridamolno treatment Exploratory Suggesting
Australian II, 1976dipyridamol + aspirincontrol Risk of bias -
Encke IB, 1976dipyridamol + aspirinplacebo Exploratory -
Encke IA, 1976dipyridamol + aspirinplacebo Exploratory -
Hamburg, 1976aspirin + dipyridamolplacebo Exploratory Negative
Zekert-III, 1977dipyridamol + aspirincontrol Risk of bias -
Weiss, 1977dipyridamol + aspirincontrol Exploratory -
Toulouse I, 1979dipyridamol + aspirincontrol Risk of bias -
Frankfurt, 1981aspirin + dipyridamolplacebo Exploratory Negative
Harjola DVT, 1982dipyridamol + aspirincontrol Risk of bias -
Chicago, 1982aspirin + dipyridamolcontrol Exploratory Negative



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