Nivolumab clinical trials immune checkpoint inhibition

Opdivo - BMS-936558 - ONO-4538 - MDX-1106

Gastric or gastro-oesophageal junction cancer (advanced)

1 trials  - ATTRACTION-2

Head and neck cancer

2 trials  - Checkmate-141 - Checkmate-651

Lung cancer (metastatic)

All type of patients:  9 trials  - CheckMate 227 (High Tumor Mutational Burden) - CheckMate 227 (nivolumab + CT) - CheckMate 227 (nivolumab alone) - CheckMate 026 - CheckMate 017 - CheckMate 057 - Checkmate 032 - CheckMate 078 - CheckMate 153

First line:  4 trials  - CheckMate 227 (High Tumor Mutational Burden) - CheckMate 227 (nivolumab + CT) - CheckMate 227 (nivolumab alone) - CheckMate 026

Second line :  8 trials  - CheckMate 017 - CheckMate 057 - Checkmate 032 - CheckMate 078 - CheckMate 153 - CheckMate 331 - CheckMate 451 - CheckMate 722

Melanoma

Adjuvant 1 - NOVARTIS:  1 trials  - CheckMate 238

Adjuvant setting:  1 trials  - CheckMate 238

Adjuvant stage III only - NOVARTIS :  1 trials  - CheckMate 238 subgroup IIIB-C

All type of patients:  7 trials  - CheckMate 238 - CheckMate 037 (Weber) - CheckMate 066 (Robert) - CheckMate 067 (nivo + ipi vs ipi) - CheckMate 067 (nivo + ipi vs nivo) - CheckMate 067 (nivo vs ipi) - Postow

First line :  4 trials  - CheckMate 066 (Robert) - CheckMate 067 (nivo + ipi vs ipi) - CheckMate 067 (nivo + ipi vs nivo) - CheckMate 067 (nivo vs ipi)

Second line (or later):  1 trials  - CheckMate 037 (Weber)

Multiple myeloma

1 trials  - CheckMate 602

Renal-cell carcinoma (advanced)

2 trials  - CheckMate-214 - Chekmate 025 (Motzer)

Urothelial carcinoma (advanced)

4 trials  - CheckMate 274 - CHECKMATE 274A - Checkmate 275 - CHECKMATE 901A