Elotuzumab Lenalidomide Dexamethasone versus Lenalidomide + Dexamethasone | |||
ELOQUENT - 1, 0 NCT01335399 | versus | Newly Diagnosed, Previously Untreated Multiple Myeloma | open label USA |
carfilzomib versus bortezomib | |||
ENDEAVOR, 2016 NCT01568866 | carfilzomib with dexamethasone versus bortezomib with dexamethasone | patients with relapsed or refractory multiplemyeloma who had one to three previous treatments | open-label |
carfilzomib versus bortezomid | |||
ECOG-ACRIN, NCT01863550 | versus | ||
CLARION, NCT01818752 | versus | ||
carfilzomib versus low-dose corticosteroids | |||
FOCUS, 2017 NCT01302392 | carfilzomib monotherapy versus low-dose corticosteroids and optional cyclophosphamide | relapsed and refractory multiple myeloma (RRMM) | open-label |
carfilzomib versus placebo (on top lenalidomide and dexamethasone) | |||
ASPIRE, 2015 NCT01080391 | carfilzomib with lenalidomide and dexamethasone versus lenalidomide and dexamethasone alone | patients with relapsed multiple myeloma | open-label |
carfilzomib lenalidomide dexamethasone versus lenalidomide and dexamethasone alone | |||
ASPIRE, 2014 NCT01080391 | carfilzomib with lenalidomide and dexamethasone versus lenalidomide and dexamethasone alone | patients with relapsed multiple myeloma | open-label |
CTDa versus MP | |||
MRC Myeloma IX, ISRCTN68454111 | CTDa versus MP | ||
elotuzumab versus placebo (on top lenalidomide and dexamethasone) | |||
ELOQUENT 2, 2015 NCT01239797 | elotuzumab plus lenalidomide and dexamethasone versus lenalidomide and dexamethasone alone | patients with Relapsed or Refractory Multiple Myeloma | open-label |
Elotuzumab Lenalidomide Dexamethasone versus Lenalidomide + Dexamethasone | |||
ELOQUENT - 2, 0 NCT01239797 | Lenalidomide + Dexamethasone +Elotuzumab versus Lenalidomide + Dexamethasone | patients with Relapsed or Refractory Multiple Myeloma | |
MPR + CPR versus Rd | |||
NR 2013, | MPR + CPR versus Rd | ||
MPR+R versus MP | |||
MM-015, NCT00405756 | MPR+R versus MP | ||
MPR+R versus MPT+T | |||
EIA06 (NCT00602641), 0 NCT00602641 | MPR+R versus MPT+T | ||
MPT versus MP | |||
IFM 01/01, | MPT versus MP | ||
IFM 99/06, NCT00367185 | MPT versus MP | ||
NCT01274403, NCT01274403 | MPT versus MP | ||
MPT+T versus MP | |||
GIMEMA, NCT00232934 | MPT+T versus MP | ||
HOVON 49, ISRCTN90692740 | MPT+T versus MP | ||
NMSG, | MPT+T versus MP | ||
TMSG, NCT00934154 | MPT+T versus MP | ||
PCAB+IFN-2a versus PCAB | |||
NR 1997, | PCAB+IFN-2a versus PCAB | ||
pembrolizumab + pomadoline + dexamethasone versus pomadoline + dexamethasone | |||
KEYNOTE-183, 2018 NCT02576977 | pembrolizumab, Pomalidomide and low-dose Dexamethasone versus Pomalidomide and low-dose Dexamethasone | refractory or relapsed and refractory Multiple Myeloma (rrMM) | open-design Follow-up duration: 7.8 mo / 8.6 mo (median) |
pembrolizumab, lenalidomide, dexametahsone versus lenalidomide, dexamethasone | |||
KEYNOTE-185, 2018 NCT02579863 | versus lenalidomide and low-dose dexamethasone | newly diagnosed and treatment naïve Multiple Myeloma who are ineligible for autologous stem cell transplant | open-design |
Rd ou Rd18 versus MPT | |||
FIRST , NCT00689936 | Rd ou Rd18 versus MPT | ||
VMP versus MP | |||
VISTA, NCT00111319 | VMP versus MP | ||
VMP + siltuximab versus VMP | |||
NCT00911859, NCT00911859 | VMP + siltuximab versus VMP | ||
VMPT+VT versus VMP | |||
NR 2010, | VMPT+VT versus VMP |