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Everolimus eluting stent
Drug eluting stent
systematic review
meta-analysis
network meta-analysis
XIENCE 5 - Abbott XIENCE V - Guidant XIENCE V - XIENCE V
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coronary artery disease
stable angina
drug-eluting stents
vs bare-metal
vs drug-eluting stents
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Description
Synopsis
Comparison
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Characteristics
Method
Risk of bias
References
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Results
Global trial result
Main results
All results
All result tag
NCT results
All cause death (17)
myocardial infarction (fatal and non fatal) (17)
CABG (17)
target lesion revascularisation (17)
MACE (17)
angiographic restenosis (17)
4 yr mortality from all causes (17)
Stent thrombosis (any, end of follow up) (17)
4 yr MI (17)
4 yr TLR (17)
4 yr death or MI (17)
4 yr stent thrombosis (17)
4y stent thrombosis (ARC) (17)
cardiac death (17)
2 yr MACE (17)
2 yr TLR (17)
2 yr Death (all cause) (17)
target-vessel revascularization (17)
late stent thrombosis (31days - 1year) (17)
in-lesion binary restenosis (17)
Acute stent thrombosis (<=24h) (17)
sub acute stent thrombosis (1-30 days) (17)
Options
Numeric
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forest plot
medians
Trial
Studied trt
Control trt
patients
tags
ROB
Trial result
All cause death
myocardial infarction (fatal and non fatal)
coronary artery disease
FUTURE I, 2004
everolimus eluting stent
bare-metal stent
negative
∞%
FUTURE II, 2006
everolimus eluting stent
bare-metal stent
Low risk of bias
-
SPIRIT I, 2005
NCT
everolimus eluting stent
bare-metal stent
Exploratory
negative
∞%
BASKET-PROVE (EES), 2010
everolimus eluting stent
bare-metal stent
suggesting
-27%
-36%
RESET, 2011
NCT
everolimus eluting stent
sirolimus eluting stent
-
PLATINUM, 2011
NCT
everolimus eluting stent
everolimus eluting stent
-
SPIRIT II, 2006
NCT
everolimus eluting stent
paclitaxel eluting stent
Risk of bias
negative
-65%
SPIRIT IV, 2010
NCT
everolimus eluting stent
paclitaxel eluting stent
Risk of bias
suggesting
-17%
-39%
SPIRIT III, 2008
NCT
everolimus eluting stent
paclitaxel eluting stent
Exploratory
suggesting
-2%
-32%
COMPARE, 2009
NCT
everolimus eluting stent
paclitaxel eluting stent
Risk of bias
suggesting
21%
-48%
SPIRIT III (small vessel subgroup), 2009
everolimus eluting stent
paclitaxel eluting stent
Exploratory
suggesting
∞%
∞%
SORT OUT IV, 2012
NCT
everolimus eluting stent
sirolimus eluting stent
Risk of bias
-
ISAR-TEST 4 (EES vs SES)
everolimus eluting stent
sirolimus eluting stent
suggesting
ESSENCE diabetes
NCT
everolimus eluting stent
sirolimus ES
-
stable angina
FUTURE I, 2004
everolimus eluting stent
bare-metal stent
negative
∞%
FUTURE II, 2006
everolimus eluting stent
bare-metal stent
Low risk of bias
-
SPIRIT I, 2005
NCT
everolimus eluting stent
bare-metal stent
Exploratory
negative
∞%
SPIRIT II, 2006
NCT
everolimus eluting stent
paclitaxel eluting stent
Risk of bias
negative
-65%
SPIRIT IV, 2010
NCT
everolimus eluting stent
paclitaxel eluting stent
Risk of bias
suggesting
-17%
-39%
SPIRIT III, 2008
NCT
everolimus eluting stent
paclitaxel eluting stent
Exploratory
suggesting
-2%
-32%
COMPARE, 2009
NCT
everolimus eluting stent
paclitaxel eluting stent
Risk of bias
suggesting
21%
-48%
SORT OUT IV, 2012
NCT
everolimus eluting stent
sirolimus eluting stent
Risk of bias
-
ISAR-TEST 4 (EES vs SES)
everolimus eluting stent
sirolimus eluting stent
suggesting
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