calcium channel blockers

systematic review meta-analysis network meta-analysis

Select acute coronary syndromeacute myocardial infarctionheart failurepost myocardial infarction uncoded clinical condition ***All type of patient       acute and long term calcium blockersacute short term calcium blockerscalcium-channel blockerslong term calcium blockers amlodipinediltiazemfelodipinenicardipinenifedipinenisoldipineverapamilisradipinemibefradil vs placebo or controlvs placebo or no treatmentvs angiotensin-converting enzyme inhibitors      

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Group by Group by... nothing pathology treatment patient comparator classe classe comparator mechanism clinical condition MA  in first nothing pathology treatment patient comparator classe classe comparator mechanism clinical condition  in second nothing pathology treatment patient comparator classe classe comparator mechanism clinical condition  in third	Description Synopsis Comparison Treatments Patients Characteristics Method Risk of bias References None Tools Indexation					Results Global trial result Main results All results All result tag NCT results	All cause death (61)confirmed myocardial infarction (38)cardiac death (12)reinfarction (9)hospitalisation for heart failure (2)cardiovascular events (1)Cardiovascular death (1)Coronary death (1) Options Numeric bar chart forest plot medians
Trial	Studied trt	Control trt	patients	tags	ROB	Trial result	All cause death	confirmed myocardial infarction
acute coronary syndrome
diltiazem
Göbel (Dutch study), 1995	diltiazem	placebo			Low risk of bias	-
DRS, 1986	diltiazem	placebo			Low risk of bias	-
nifedipine
HINT (nifedipine vs metoprolol), 1988	nifedipine	metoprolol				-
acute myocardial infarction
diltiazem
Machecourt, 1986	diltiazem					negative
Zannad, 1988	diltiazem	placebo			Low risk of bias	negative
MDPIT, 1988	diltiazem	placebo			Low risk of bias	negative
Gibson, 1986	diltiazem	placebo			Low risk of bias	negative
nifedipine
MI study group, 1979	nifedipine					-
Muller, 1984	nifedipine				Low risk of bias	negative
Gordon, 1984	nifedipine					negative
Gottlieb, 1988	nifedipine	placebo			Low risk of bias	negative
Walker, 1988	nifedipine	placebo			Low risk of bias	negative
TRENT (Wilcox), 1986	nifedipine	placebo			Low risk of bias	negative
Loogna, 1985	nifedipine	placebo			Low risk of bias	negative
Erbel, 1988	nifedipine	placebo			Low risk of bias	negative
SPRINT II, 1993	nifedipine	placebo			Low risk of bias	negative
SPRINT I, 1988	nifedipine	placebo			Low risk of bias	negative
Eisenberg, 1985	nifedipine	placebo			Low risk of bias	negative
Bradagan, 1986	nifedipine	placebo			Low risk of bias	negative
Jaffe, 1987	nifedipine	placebo				negative
Sirnes, 1984	nifedipine	placebo			Low risk of bias	negative
verapamil
Bussman, 1984	verapamil	control				negative
CRIS, 1996	verapamil	placebo			Low risk of bias	negative
DAVIT II, 1990	verapamil	placebo			Low risk of bias	negative
Crea, 1985	verapamil	placebo				negative
DAVIT I, 1984	verapamil	placebo			Low risk of bias	-
Danish study, 1984	verapamil	placebo			Low risk of bias	negative
heart failure
amlodipine
Packer, 1991	amlodipine	control			Low risk of bias	-
Smith, 1994	amlodipine	control			Low risk of bias	-
Udelson, 1996	amlodipine	control			Low risk of bias	-
Binkley, 1996	amlodipine	control			Low risk of bias	-
Ghali, 1997	amlodipine	control			Low risk of bias	-
PRAISE II , 2000	Amlodipine	placebo			Low risk of bias	negative
PRAISE, 1996	amlodipine	placebo			Low risk of bias	negative
diltiazem
DiDi, 1996	diltiazem	placebo			Low risk of bias	negative
Liao , 1998	Diltiazem	placebo			Exploratory	suggesting
felodipine
Kassis, 1990	felodipine	placebo			Low risk of bias	-
Littler, 1995	Felodipine	placebo			Low risk of bias	negative
Kassis, 1987	felodipine	placebo			Low risk of bias	-
VHeFT III, 1997	felodipine	placebo			Low risk of bias	negative
De Vries, 1995	felodipine	enalapril			Low risk of bias	-
Dunselman, 1990	felodipine	enalapril			Low risk of bias	-
isradipine
Van den Toren, 1996	isradipine	placebo			Low risk of bias	-
mibefradil
MACH 1, 2000	mibefradil	placebo			Low risk of bias	suggesting
nicardipine
Gheorghiade, 1991	nicardipine	control			Low risk of bias	-
Abrams, 1993	nicardipine	control			Low risk of bias	-
nisoldipine
Gaudron, 1996	Nisoldipine	placebo			Exploratory	-
Rousseau, 1994	nisoldipine	placebo			Low risk of bias	-
Schofer, 1990	nisoldipine	captopril			Low risk of bias	-
post myocardial infarction
diltiazem
MDPIT, 1988	diltiazem	placebo			Low risk of bias	negative
nifedipine
MI study group, 1979	nifedipine					-
SPRINT I, 1988	nifedipine	placebo			Low risk of bias	negative
SPRINT II, 1993	nifedipine	placebo			Low risk of bias	negative
verapamil
DAVIT I, 1984	verapamil	placebo			Low risk of bias	-
DAVIT II, 1990	verapamil	placebo			Low risk of bias	negative
CRIS, 1996	verapamil	placebo			Low risk of bias	negative
Danish study, 1984	verapamil	placebo			Low risk of bias	negative