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Nisoldipine
calcium channel blockers
systematic review
meta-analysis
network meta-analysis
Bay K 5552
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diabetes type 2
heart failure
hypertension
percutaneous coronary intervention
calcium-channel blockers
vs control or placebo
vs placebo or no treatment
vs angiotensin-converting enzyme inhibitors
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Description
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NCT results
All cause death (5)
cardiovascular events (5)
Cardiovascular death (5)
Total exercise duration (s) (5)
Time to angina onset (s) (5)
Time to 1 mm ST depression (s) (5)
Angina episodes per week (5)
Nitroglycerin use per week (5)
Coronary death (3)
hospitalisation for heart failure (3)
stroke (fatal and non fatal) (2)
Non fatal MI (2)
Non fatal stroke (2)
CV death, MI hospitalization for HF (2)
Time to limiting angina (s) (2)
myocardial infarction (fatal and non fatal) (1)
microvascular events (1)
Coronary event (1)
Heart failure (1)
Fatal stroke (1)
Fatal MI (1)
End stage renal disease (1)
Diabetes onset (1)
Angina (1)
Revascularization (1)
Peripheral arterial disease (1)
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medians
Trial
Studied trt
Control trt
patients
tags
ROB
Trial result
All cause death
cardiovascular events
diabetes type 2
ABCD (hypertension), 1998
nisoldipine
enalapril
Low risk of bias
suggesting
-23%
-57%
heart failure
Gaudron, 1996
Nisoldipine
placebo
Exploratory
-
Rousseau, 1994
nisoldipine
placebo
Low risk of bias
-
Schofer, 1990
nisoldipine
captopril
Low risk of bias
-
hypertension
ABCD (hypertension), 1998
nisoldipine
enalapril
Low risk of bias
suggesting
-23%
-57%
percutaneous coronary intervention
Dens (CAPARES), 2000
nisoldipine
placebo
Low risk of bias
suggesting
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