new version V2017

Lisinopril angiotensin-Converting Enzyme Inhibitors

MK-521 - Prinivil - Zestril - Lysinopril - Lisinopril      

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TrialStudied treatmentControl treatmentpatientsROBResultNCT

acute myocardial infarction

GISSI 3, 1994lisinoprilplacebo Risk of bias -

atrial fibrillation

Van den Burg, 1995lisinoprilplaceboNegative
GISSI-3 (AF ancillary study), 2003lisinoprilplaceboNegative

diabetes type 2

ALLHAT (lisi vs chlor, diabetic subgroup), 2002lisinoprilchlorthalidone Exploratory Negative

heart failure

Rucinska-c (lisinopril), 1000lisinoprilcontrolNegative
International Study Group (Lewis), 1989lisinoprilplacebo Exploratory -
Zwehl, 1990lisinoprilcontrolNegative
Giles, 1990lisinoprilcontrolNegative
Gilbert, 1993lisinoprilplaceboNegative
ATLAS, 1999lisinoprillisinopril Low risk of bias -

hypertension

ALLHAT (ACEI vs amlodipine), 2002lisinoprilamlodipineSuggesting
ALLHAT (lisi vs chlor, diabetic subgroup), 2002lisinoprilchlorthalidone Exploratory Negative
ALLHAT (ACEI vs chlorthalidone), 2002lisinoprildiuretics Low risk of bias Negative