Clinical trials of sirolimus eluting stent

Trial	Studied treatment	Control treatment	ROB	Result	NCT
acute myocardial infarction
Di Lorenzo et al., 2005	sirolimus eluting stent	paclitaxel eluting stent		Negative
TYPHOON, 2006	sirolimus eluting stent	bare-metal stent		Suggesting	NCT00232830
PROSIT, 2006	sirolimus eluting stent	paclitaxel eluting stent		Negative
SESAMI, 2007	sirolimus eluting stent	bare-metal stent	Risk of bias	Suggesting	NCT00288210
Díaz de la Llera, 2007	sirolimus eluting stent	bare-metal stent		-
MISSION, 2008	sirolimus eluting stent	bare-metal stent	Risk of bias	Suggesting	ISRCTN62825862
DEBATER (SES vs BMS), 2009	sirolimus eluting stent	bare-metal stent		Suggesting
Juwana, 2009	sirolimus eluting stent	paclitaxel eluting stent		Negative	ISRCTN90526229
coronary artery disease
CRISTAL	sirolimus eluting stent	PTCA		-	NCT00323895
RAVEL, 2002	sirolimus eluting stent	bare-metal stent		Suggesting	NCT00233805
SIRIUS, 2003	sirolimus eluting stent	bare-metal stent	Low risk of bias	Suggesting	NCT00232765
E-SIRIUS, 2003	sirolimus eluting stent	bare-metal stent		Suggesting	NCT00235144
Pasceri, 2003	sirolimus eluting stent	bare-metal stent		-
SIRIUS (diabetics), 2003	sirolimus eluting stent	bare-metal stent		-
C-SIRIUS, 2004	sirolimus eluting stent	bare-metal stent		Suggesting	NCT00381420
SES-SMART, 2004	sirolimus eluting stent	bare-metal stent		Suggesting
Ravel (diabetics), 2004	sirolimus eluting stent	bare-metal stent		Suggesting
ISAR-DESIRE (SES vs PTCA), 2005	sirolimus eluting stent	balloon angioplasty		Suggesting
DIABETES, 2005	sirolimus eluting stent	bare-metal stent		Suggesting
Pache et al, 2005	sirolimus eluting stent	bare-metal stent		Suggesting
DECODE, 2005	sirolimus eluting stent	bare-metal stent		Suggesting	NCT00489164
SES-SMARt (diabetics), 2005	sirolimus eluting stent	bare-metal stent		Suggesting
TAXi, 2005	sirolimus eluting stent	paclitaxel eluting stent	Risk of bias	Negative
ISAR-DESIRE (SES vs PES), 2005	sirolimus eluting stent	paclitaxel eluting stent		Suggesting
ISAR-DIABETES, 2005	sirolimus eluting stent	paclitaxel eluting stent		Negative
SIRTAX (Windecker), 2005	sirolimus eluting stent	paclitaxel eluting stent	Risk of bias	Suggesting
CORPAL, 2005	sirolimus eluting stent	paclitaxel eluting stent		Negative
BASKET (vs paclitaxel), 2005	sirolimus eluting stent	paclitaxel eluting stent		Negative
Di Lorenzo et al., 2005	sirolimus eluting stent	paclitaxel eluting stent		Negative
SIRTAX (small vessels subgroup), 2005	sirolimus eluting stent	paclitaxel eluting stent		Suggesting
SIRTAX diabetics, 2005	sirolimus eluting stent	paclitaxel eluting stent		Negative	NCT00297661
PRISON II, 2006	sirolimus eluting stent	bare-metal stent	Risk of bias	Suggesting	NCT00258596
SCANDSTENT, 2006	sirolimus eluting stent	bare-metal stent		Suggesting	NCT00151658
TYPHOON, 2006	sirolimus eluting stent	bare-metal stent		Suggesting	NCT00232830
RRISC, 2006	sirolimus eluting stent	bare-metal stent	Risk of bias	Suggesting	NCT00263263
SCANDSTENT (subgroup), 2006	sirolimus eluting stent	bare-metal stent	Exploratory	Suggesting
REALITY, 2006	sirolimus eluting stent	paclitaxel eluting stent	Risk of bias	Suggesting	NCT00235092
ISAR-SMART 3, 2006	sirolimus eluting stent	paclitaxel eluting stent		Negative	NCT00146575
Zhang (SES vs PES), 2006	sirolimus eluting stent	paclitaxel eluting stent	Exploratory	Negative
LONG DES II, 2006	sirolimus eluting stent	paclitaxel eluting stent	Risk of bias	Suggesting
PROSIT, 2006	sirolimus eluting stent	paclitaxel eluting stent		Negative
Cervinka, 2006	sirolimus eluting stent	paclitaxel eluting stent		Negative
Han, 2006	sirolimus eluting stent	paclitaxel eluting stent		Negative
ISAR-TEST-1, 2006	sirolimus eluting stent	paclitaxel eluting stent	Risk of bias	Negative	NCT00140530
REALITY (diabetics), 2006	sirolimus eluting stent	paclitaxel eluting stent		Negative
Kochiadakis, 2007	sirolimus eluting stent	bare-metal stent	Exploratory	-
SESAMI, 2007	sirolimus eluting stent	bare-metal stent	Risk of bias	Suggesting	NCT00288210
SCORPIUS, 2007	sirolimus eluting stent	bare-metal stent		Suggesting	NCT00495898
Ortolani et al, 2007	sirolimus eluting stent	bare-metal stent		-
Díaz de la Llera, 2007	sirolimus eluting stent	bare-metal stent		-
SISR, 2007	sirolimus eluting stent	brachytherapy	Risk of bias	Suggesting	NCT00231257
Petronio et al, 2007	sirolimus eluting stent	paclitaxel eluting stent		Negative
Pan, 2007	sirolimus eluting stent	paclitaxel eluting stent	Exploratory	Suggesting
MISSION, 2008	sirolimus eluting stent	bare-metal stent	Risk of bias	Suggesting	ISRCTN62825862
DESSERT, 2008	sirolimus eluting stent	bare-metal stent	Exploratory	Suggesting
Tomai, 2008	sirolimus eluting stent	paclitaxel eluting stent		-
SORT OUT II, 2008	sirolimus eluting stent	paclitaxel eluting stent		Negative	NCT00388934
Wessely, 2008	sirolimus eluting stent	paclitaxel eluting stent	Exploratory	-
Kim, 2008	sirolimus eluting stent	paclitaxel eluting stent		Negative
DES-DIABETES, 2008	sirolimus eluting stent	paclitaxel eluting stent	Risk of bias	Suggesting
RIBS-II, 2008	sirolimus eluting stent	PTCA		Suggesting
DEBATER (SES vs BMS), 2009	sirolimus eluting stent	bare-metal stent		Suggesting
Thiele, 2009	PCI withsirolimus ES	MIDCAB	Risk of bias	-	NCT00299429
ISAR-LEFT-MAIN, 2009	sirolimus eluting stent	paclitaxel eluting stent		Negative	NCT00133237
GISSOC II, 2010	sirolimus eluting stent	bare-metal stent	Exploratory	Suggesting	NCT00220558
BASKET-PROVE (SES), 2010	sirolimus eluting stent	bare-metal stent	Risk of bias	Suggesting	ISRCTN72444640
ISAR-DESIRE-2, 2010	sirolimus eluting stent	paclitaxel eluting stent	Risk of bias	-	NCT00598715
PRECOMBAT, 2011	sirolimus eluting stent	CABG		-	NCT00422968
TAxi (diabetics)	sirolimus eluting stent	paclitaxel eluting stent		-
Gao ongoing	sirolimus eluting stent	Firebird eluting stent		-	NCT00887211
MIDCAB Versus DES in Proximal LAD Lesions ongoing	sirolimus eluting stent	CABG		-	NCT00299429
Munich Study ongoing	sirolimus eluting stent	CABG		-
FOCUS ongoing	sirolimus eluting stent	cutting ballon angioplasty		-	NCT00485004
DES-ISR ongoing	sirolimus eluting stent	paclitaxel eluting stent		-	NCT00485030
Lipsia-Yukon-DM ongoing	sirolimus eluting stent	paclitaxel eluting stent		-	NCT00368953
BASKET-PROVE, 2008 ongoing	sirolimus eluting stent	bare-metal stent		-
stable angina
RAVEL, 2002	sirolimus eluting stent	bare-metal stent		Suggesting	NCT00233805
SIRIUS, 2003	sirolimus eluting stent	bare-metal stent	Low risk of bias	Suggesting	NCT00232765
E-SIRIUS, 2003	sirolimus eluting stent	bare-metal stent		Suggesting	NCT00235144
Pasceri, 2003	sirolimus eluting stent	bare-metal stent		-
C-SIRIUS, 2004	sirolimus eluting stent	bare-metal stent		Suggesting	NCT00381420
SES-SMART, 2004	sirolimus eluting stent	bare-metal stent		Suggesting
DIABETES, 2005	sirolimus eluting stent	bare-metal stent		Suggesting
Pache et al, 2005	sirolimus eluting stent	bare-metal stent		Suggesting
DECODE, 2005	sirolimus eluting stent	bare-metal stent		Suggesting	NCT00489164
TAXi, 2005	sirolimus eluting stent	paclitaxel eluting stent	Risk of bias	Negative
ISAR-DESIRE (SES vs PES), 2005	sirolimus eluting stent	paclitaxel eluting stent		Suggesting
ISAR-DIABETES, 2005	sirolimus eluting stent	paclitaxel eluting stent		Negative
SIRTAX (Windecker), 2005	sirolimus eluting stent	paclitaxel eluting stent	Risk of bias	Suggesting
CORPAL, 2005	sirolimus eluting stent	paclitaxel eluting stent		Negative
BASKET (vs paclitaxel), 2005	sirolimus eluting stent	paclitaxel eluting stent		Negative
Di Lorenzo et al., 2005	sirolimus eluting stent	paclitaxel eluting stent		Negative
PRISON II, 2006	sirolimus eluting stent	bare-metal stent	Risk of bias	Suggesting	NCT00258596
SCANDSTENT, 2006	sirolimus eluting stent	bare-metal stent		Suggesting	NCT00151658
REALITY, 2006	sirolimus eluting stent	paclitaxel eluting stent	Risk of bias	Suggesting	NCT00235092
ISAR-SMART 3, 2006	sirolimus eluting stent	paclitaxel eluting stent		Negative	NCT00146575
Zhang (SES vs PES), 2006	sirolimus eluting stent	paclitaxel eluting stent	Exploratory	Negative
LONG DES II, 2006	sirolimus eluting stent	paclitaxel eluting stent	Risk of bias	Suggesting
Cervinka, 2006	sirolimus eluting stent	paclitaxel eluting stent		Negative
Han, 2006	sirolimus eluting stent	paclitaxel eluting stent		Negative
ISAR-TEST-1, 2006	sirolimus eluting stent	paclitaxel eluting stent	Risk of bias	Negative	NCT00140530
Kochiadakis, 2007	sirolimus eluting stent	bare-metal stent	Exploratory	-
SCORPIUS, 2007	sirolimus eluting stent	bare-metal stent		Suggesting	NCT00495898
Ortolani et al, 2007	sirolimus eluting stent	bare-metal stent		-
Petronio et al, 2007	sirolimus eluting stent	paclitaxel eluting stent		Negative
DESSERT, 2008	sirolimus eluting stent	bare-metal stent	Exploratory	Suggesting
Tomai, 2008	sirolimus eluting stent	paclitaxel eluting stent		-
Kim, 2008	sirolimus eluting stent	paclitaxel eluting stent		Negative
Thiele, 2009	PCI withsirolimus ES	MIDCAB	Risk of bias	-	NCT00299429
ISAR-LEFT-MAIN, 2009	sirolimus eluting stent	paclitaxel eluting stent		Negative	NCT00133237
GISSOC II, 2010	sirolimus eluting stent	bare-metal stent	Exploratory	Suggesting	NCT00220558
MIDCAB Versus DES in Proximal LAD Lesions ongoing	sirolimus eluting stent	CABG		-	NCT00299429
FOCUS ongoing	sirolimus eluting stent	cutting ballon angioplasty		-	NCT00485004
DES-ISR ongoing	sirolimus eluting stent	paclitaxel eluting stent		-	NCT00485030
Lipsia-Yukon-DM ongoing	sirolimus eluting stent	paclitaxel eluting stent		-	NCT00368953

Sirolimus eluting stent Drug eluting stent Description Results

Group by...

acute myocardial infarction

coronary artery disease

stable angina

Sirolimus eluting stent Drug eluting stent
Description Results