new version V2017

Drug eluting stent
Description Results

Biolimus eluting stent - Everolimus eluting stent - Paclitaxel eluting stent - Sirolimus eluting stent - Zotarolimus eluting stent      

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TrialStudied treatmentControl treatmentpatientsROBResultNCT

coronary artery disease

abciximab
Kim, 2010abciximab-coated stentbare-metal stent Exploratory -
biolimus eluting stent
LEADERS, 2008biolimus eluting stentsirolimus eluting stentNegativeNCT00389220
candesartan
SYNTAX (unprotected left main sub group), 2009DESCABG Risk of bias Suggesting
dactinomycin eluting stent
ACTION, 2004dactinomycin eluting stentbare-metal stentSuggesting
drug-eluting stents
Hong, 2005PCI withdrug-eluting stentsCABG Risk of bias -
DEDICATION, 2008drug-eluting stentsbare-metal stent Risk of bias SuggestingNCT00192868
Boudriot, 2008DESCABG Exploratory Negative
GENIUS-STEMI, 2009Genous stentbare-metal stent Exploratory Negative
PASEO, 2009drug-eluting stentsbare-metal stent -
FREEDOM, 2012PCI with drug-eluting stentsCABG Risk of bias Negative NCT00086450
ISAR-CABG ongoing drug-eluting stentsbare-metal stent - NCT00611910
Leipzig ongoing drug-eluting stentsCABG - NCT00176397
VA CARDS ongoing PCI withdrug-eluting stentsCABG Risk of bias - NCT00326196
everolimus eluting stent
ISAR-TEST 4 (EES vs SES)everolimus eluting stentsirolimus eluting stentSuggesting
FUTURE I, 2004everolimus eluting stentbare-metal stentNegative
SPIRIT I, 2005everolimus eluting stentbare-metal stent Exploratory NegativeNCT00180453
FUTURE II, 2006everolimus eluting stentbare-metal stent -
SPIRIT II, 2006everolimus eluting stentpaclitaxel eluting stent Risk of bias NegativeNCT00180310
SPIRIT III, 2008everolimus eluting stentpaclitaxel eluting stent Exploratory SuggestingNCT00180479
COMPARE, 2009everolimus eluting stentpaclitaxel eluting stent Risk of bias SuggestingNCT01016041
SPIRIT III (small vessel subgroup), 2009everolimus eluting stentpaclitaxel eluting stent Exploratory Suggesting
BASKET-PROVE (EES), 2010everolimus eluting stentbare-metal stentSuggestingISRCTN72444640
SPIRIT IV, 2010everolimus eluting stentpaclitaxel eluting stent Risk of bias SuggestingNCT00307047
PLATINUM, 2011everolimus eluting stenteverolimus eluting stent - NCT00823212
RESET, 2011everolimus eluting stentsirolimus eluting stent - NCT01035450
SORT OUT IV, 2012everolimus eluting stentsirolimus eluting stent Risk of bias - NCT00552877
LEFT-MAIN-2 ongoing everolimus eluting stentzotarolimus eluting stent - NCT00598637
paclitaxel
TAXUS V small vessels sub groupspaclitaxel eluting stentbare-metal stent -
PATENCY, 2002paclitaxel, non-polymeric eluting stentbare-metal stentNegative
TAXUS I, 2003paclitaxel eluting stentbare-metal stentNegative
TAXUS II, 2003paclitaxel eluting stentbare-metal stentSuggestingNCT00299026
ASPECT, 2003paclitaxel, non-polymeric eluting stentbare-metal stentSuggestingNCT00196079
TAXUS II (diabetics), 2003paclitaxel eluting stentbare-metal stentSuggesting
TAXUS IV, 2004paclitaxel eluting stentbare-metal stent Low risk of bias SuggestingNCT00292474
ELUTES, 2004paclitaxel, non-polymeric eluting stentbare-metal stentNegative
DELIVER, 2004paclitaxel, non-polymeric eluting stentbare-metal stent Risk of bias Negative
SCORE, 2004paclitaxel eluting stentbare-metal stentSuggesting
ISAR-DESIRE (PES vs PTCA), 2005paclitaxel eluting stentballoon angioplastySuggesting
TAXUS V (all patients), 2005paclitaxel eluting stentbare-metal stentSuggestingNCT00301522
TAXUS VI, 2005paclitaxel eluting stentbare-metal stentSuggestingNCT00297804
TAXUS IV (diabetics), 2005paclitaxel eluting stentbare-metal stentSuggestingNCT00292474
TAXUS V (diabetics), 2005paclitaxel eluting stentbare-metal stentSuggesting
TAXUS VI (diabetics), 2005paclitaxel eluting stentbare-metal stentSuggestingNCT00297804
PASSION, 2006paclitaxel eluting stentbare-metal stent Risk of bias NegativeISRCTN65027270
HAAMU-STENT, 2006paclitaxel eluting stentbare-metal stent Exploratory Negative
TAXUS V ISR, 2006paclitaxel eluting balloonbrachytherapy Risk of bias - NCT00287573
ISAR-test (diabetics), 2006paclitaxel eluting stentsirolimus eluting stent Risk of bias -
Erglis, 2007paclitaxel eluting stentbare-metal stentSuggesting
HORIZONS-AMI Stent, 2008paclitaxel eluting stentbare-metal stentSuggesting
SOS, 2008paclitaxel eluting stentbare-metal stent Exploratory SuggestingNCT00247208
SYNTAX, 2009paclitaxel eluting stentCABG Risk of bias Suggesting NCT00114972
BASKET-SAVAGE ongoing paclitaxel eluting stentbare-metal stent - NCT00595647
VELETI ongoing paclitaxel eluting stentmedical treatment - NCT00289835
PEPCAD IV ongoing paclitaxel eluting balloonpaclitaxel eluting stent - NCT00462631
FRE-RACE ongoing paclitaxel eluting stentsirolimus eluting stent - NCT00130546
PERSEUS Workhorse, 2010 ongoing paclitaxel eluting stentpaclitaxel eluting stent - NCT00484315
PCI
COMBAT ongoing PCICABG -
Korean Randomized Study ongoing PCICABG -
REVASCULARIZE ongoing PCICABG -
sirolimus eluting stent
CRISTALsirolimus eluting stentPTCA - NCT00323895
RAVEL, 2002sirolimus eluting stentbare-metal stentSuggestingNCT00233805
SIRIUS, 2003sirolimus eluting stentbare-metal stent Low risk of bias SuggestingNCT00232765
E-SIRIUS, 2003sirolimus eluting stentbare-metal stentSuggestingNCT00235144
Pasceri, 2003sirolimus eluting stentbare-metal stent -
SIRIUS (diabetics), 2003sirolimus eluting stentbare-metal stent -
C-SIRIUS, 2004sirolimus eluting stentbare-metal stentSuggestingNCT00381420
SES-SMART, 2004sirolimus eluting stentbare-metal stentSuggesting
Ravel (diabetics), 2004sirolimus eluting stentbare-metal stentSuggesting
ISAR-DESIRE (SES vs PTCA), 2005sirolimus eluting stentballoon angioplastySuggesting
DIABETES, 2005sirolimus eluting stentbare-metal stentSuggesting
Pache et al, 2005sirolimus eluting stentbare-metal stentSuggesting
DECODE, 2005sirolimus eluting stentbare-metal stentSuggestingNCT00489164
SES-SMARt (diabetics), 2005sirolimus eluting stentbare-metal stentSuggesting
TAXi, 2005sirolimus eluting stentpaclitaxel eluting stent Risk of bias Negative
ISAR-DESIRE (SES vs PES), 2005sirolimus eluting stentpaclitaxel eluting stentSuggesting
ISAR-DIABETES, 2005sirolimus eluting stentpaclitaxel eluting stentNegative
SIRTAX (Windecker), 2005sirolimus eluting stentpaclitaxel eluting stent Risk of bias Suggesting
CORPAL, 2005sirolimus eluting stentpaclitaxel eluting stentNegative
BASKET (vs paclitaxel), 2005sirolimus eluting stentpaclitaxel eluting stentNegative
Di Lorenzo et al., 2005sirolimus eluting stentpaclitaxel eluting stentNegative
SIRTAX diabetics, 2005sirolimus eluting stentpaclitaxel eluting stentNegativeNCT00297661
SIRTAX (small vessels subgroup), 2005sirolimus eluting stentpaclitaxel eluting stentSuggesting
PRISON II, 2006sirolimus eluting stentbare-metal stent Risk of bias SuggestingNCT00258596
SCANDSTENT, 2006sirolimus eluting stentbare-metal stentSuggestingNCT00151658
TYPHOON, 2006sirolimus eluting stentbare-metal stentSuggestingNCT00232830
RRISC, 2006sirolimus eluting stentbare-metal stent Risk of bias SuggestingNCT00263263
SCANDSTENT (subgroup), 2006sirolimus eluting stentbare-metal stent Exploratory Suggesting
REALITY, 2006sirolimus eluting stentpaclitaxel eluting stent Risk of bias SuggestingNCT00235092
ISAR-SMART 3, 2006sirolimus eluting stentpaclitaxel eluting stentNegativeNCT00146575
Zhang (SES vs PES), 2006sirolimus eluting stentpaclitaxel eluting stent Exploratory Negative
LONG DES II, 2006sirolimus eluting stentpaclitaxel eluting stent Risk of bias Suggesting
PROSIT, 2006sirolimus eluting stentpaclitaxel eluting stentNegative
Cervinka, 2006sirolimus eluting stentpaclitaxel eluting stentNegative
Han, 2006sirolimus eluting stentpaclitaxel eluting stentNegative
ISAR-TEST-1, 2006sirolimus eluting stentpaclitaxel eluting stent Risk of bias NegativeNCT00140530
REALITY (diabetics), 2006sirolimus eluting stentpaclitaxel eluting stentNegative
Kochiadakis, 2007sirolimus eluting stentbare-metal stent Exploratory -
SESAMI, 2007sirolimus eluting stentbare-metal stent Risk of bias SuggestingNCT00288210
SCORPIUS, 2007sirolimus eluting stentbare-metal stentSuggestingNCT00495898
Ortolani et al, 2007sirolimus eluting stentbare-metal stent -
Díaz de la Llera, 2007sirolimus eluting stentbare-metal stent -
SISR, 2007sirolimus eluting stentbrachytherapy Risk of bias SuggestingNCT00231257
Petronio et al, 2007sirolimus eluting stentpaclitaxel eluting stentNegative
Pan, 2007sirolimus eluting stentpaclitaxel eluting stent Exploratory Suggesting
MISSION, 2008sirolimus eluting stentbare-metal stent Risk of bias SuggestingISRCTN62825862
DESSERT, 2008sirolimus eluting stentbare-metal stent Exploratory Suggesting
Tomai, 2008sirolimus eluting stentpaclitaxel eluting stent -
SORT OUT II, 2008sirolimus eluting stentpaclitaxel eluting stentNegativeNCT00388934
Kim, 2008sirolimus eluting stentpaclitaxel eluting stentNegative
DES-DIABETES, 2008sirolimus eluting stentpaclitaxel eluting stent Risk of bias Suggesting
Wessely, 2008sirolimus eluting stentpaclitaxel eluting stent Exploratory -
RIBS-II, 2008sirolimus eluting stentPTCASuggesting
DEBATER (SES vs BMS), 2009sirolimus eluting stentbare-metal stentSuggesting
Thiele, 2009PCI withsirolimus ESMIDCAB Risk of bias - NCT00299429
ISAR-LEFT-MAIN, 2009sirolimus eluting stentpaclitaxel eluting stentNegativeNCT00133237
GISSOC II, 2010sirolimus eluting stentbare-metal stent Exploratory Suggesting NCT00220558
BASKET-PROVE (SES), 2010sirolimus eluting stentbare-metal stent Risk of bias SuggestingISRCTN72444640
ISAR-DESIRE-2, 2010sirolimus eluting stentpaclitaxel eluting stent Risk of bias - NCT00598715
PRECOMBAT, 2011sirolimus eluting stentCABG - NCT00422968
TAxi (diabetics)sirolimus eluting stentpaclitaxel eluting stent -
Gao ongoing sirolimus eluting stentFirebird eluting stent - NCT00887211
MIDCAB Versus DES in Proximal LAD Lesions ongoing sirolimus eluting stentCABG - NCT00299429
Munich Study ongoing sirolimus eluting stentCABG -
FOCUS ongoing sirolimus eluting stentcutting ballon angioplasty - NCT00485004
DES-ISR ongoing sirolimus eluting stentpaclitaxel eluting stent - NCT00485030
Lipsia-Yukon-DM ongoing sirolimus eluting stentpaclitaxel eluting stent - NCT00368953
BASKET-PROVE, 2008 ongoing sirolimus eluting stentbare-metal stent -
zotarolimus eluting stent
ENDEAVOR II, 2006zotarolimus eluting stentbare-metal stentSuggesting
ENDEAVOR III, 2006zotarolimus eluting stentsirolimus eluting stentSuggesting NCT00217256
ZoMaxx I, 2008zotarolimus eluting stentpaclitaxel eluting stent -
ENDEAVOR IV, 2009zotarolimus eluting stentpaclitaxel eluting stent Risk of bias SuggestingNCT00217269
ZEST AMI (vs PES), 2009zotarolimus eluting stentpaclitaxel eluting stent Risk of bias NegativeNCT00422565
ZEST (vs PES), 2009zotarolimus eluting stentpaclitaxel eluting stentSuggestingNCT00418067
ZEST (vs SES), 2009zotarolimus eluting stentsirolimus eluting stent Risk of bias NegativeNCT00418067
ZEST AMI (vs SES), 2009zotarolimus eluting stentsirolimus eluting stentNegativeNCT00422565
RESOLUTE All comers, 2010zotarolimus eluting stenteverolimus eluting stent Risk of bias NegativeNCT00617084.)
SORT-OUT-3, 2010zotarolimus eluting stentsirolimus eluting stent Risk of bias Negative NCT00660478
TWENTE, 2012zotarolimus eluting stenteverolimus eluting stent - NCT01066650
PROTECT, 2012zotarolimus eluting stentsirolimus eluting stent Risk of bias - NCT00476957
ZoMaxx phase 2 ongoing zotarolimus eluting stentpaclitaxel eluting stent - NCT00140101
DIABEDES IV ongoing zotarolimus eluting stentsirolimus eluting stent - NCT00552994
PRISON III, 2007 ongoing zotarolimus eluting stentsirolimus eluting stent - NCT00428454



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