Trial | Studied treatment | Control treatment | patients | ROB | Result | NCT |
---|
|
|
MIRACL (AF ancillary study), 2001 | atorvastatin | placebo | | Exploratory | Negative | |
MIRACL (sub-group) (Schwartz), 2004 | atorvastatin | placebo | | Exploratory | Suggesting | |
Ozaydin, 2006 | atorvastatin | control | | Exploratory | Suggesting | |
Dernellis, 2006 | atorvastatin | placebo | | Exploratory | Suggesting | |
ARMYDA-3 (AF ancillary study), 2006 | atorvastatin | placebo | | | Suggesting | |
Chello, 2006 | atorvastatin | placebo | | Exploratory | Negative | |
Almroth, 2009 | atorvastatin | placebo | | Risk of bias | Suggesting | |
STOP-AF ongoing | atorvastatin | placebo | | | - | NCT00252967 |
|
CHARM (AF ancillary study), 2005 | candesartan | placebo | | | Suggesting | |
CAPRAF (Tveit), 2007 | candesartan | placebo | | Risk of bias | - | NCT00130975 |
|
Ueng, 2003 | enalapril | control | | | Suggesting | |
SOLVD (AF ancillary study), 2003 | enalapril | placebo | | | Suggesting | |
|
VA HIT (AF ancillary study), 1999 | gemfibrozil | placebo | | Exploratory | Negative | |
|
Madrid, 2002 | irbesartan | control | | | Suggesting | |
ACTIVE I, 2009 | irbesartan | placebo | | Low risk of bias | Suggesting | NCT00249795 |
|
Van den Burg, 1995 | lisinopril | placebo | | | Negative | |
GISSI-3 (AF ancillary study), 2003 | lisinopril | placebo | | | Negative | |
|
LIFE (AF ancillary study), 2005 | losartan | atenolol | | | Suggesting | |
|
ANTIPAF ongoing | olmesartan | placebo | | Low risk of bias | - | NCT00098137 |
|
Tveit, 2004 | pravastatin | control | | Exploratory | Negative | |
|
Brown ongoing | ramipril | placebo | | | - | NCT00141778 |
|
GISSI HF (subgroup and ancillary study), 2009 | rosuvastatin | placebo | | Exploratory | Negative | NCT00336336 |
|
Val-HeFT (AF ancillary study), 2003 | valsartan | placebo | | | Suggesting | |
GISSI-AF (Disertori), 2009 | valsartan | placebo | | Low risk of bias | Negative | NCT00376272 |
|
|
Liao, 2002 | AHA 2 diet | AHA 1 diet | | Exploratory | Negative | |
|
GRACE - ORIGIN (glargine), 2012 | insulin glargine | placebo | | | - | |
|
Eriksson, 2006 | glipizide | placebo | | Exploratory | Negative | |
|
Jarret, 1979 | lifestyle modification + metformin | control | | Exploratory | Negative | |
Sirtori, 1984 | metformin | placebo | | | - | |
Giugliano, 1993 | metformin | placebo | | | - | |
Crave, 1995 | metformin | placebo | | | - | |
Charles, 1998 | metformin | placebo | | | Negative | |
Morel, 1999 | metformin | placebo | | | - | |
Li, 1999 | metformin | placebo | | Exploratory | Negative | |
Pasquali, 2000 | metformin | placebo | | | - | |
Charles, 2000 | metformin | placebo | | | - | |
Moghetti, 2000 | metformin | placebo | | | - | |
Freemark, 2001 | metformin | placebo | | | - | |
Lehtovirta, 2001 | metformin | placebo | | | Negative | |
Ng, 2001 | metformin | placebo | | | - | |
Kay, 2001 | metformin | placebo | | | - | |
Kocak, 2002 | metformin | placebo | | | - | |
US-DPP (metformin) (Knowler), 2002 | metformin | placebo | | Low risk of bias | Negative | |
Fleming, 2002 | metformin | placebo | | | - | |
Sturrock, 2002 | metformin | placebo | | | - | |
Kelly, 2002 | metformin | placebo | | | - | |
EDIT (Holman), 2003 | metformin | placebo | | | - | |
Choux, 2003 | metformin | placebo | | | - | |
Baillargeon, 2004 | metformin | placebo | | | - | |
Rodriguez-Moctezuma, 2004 | metformin | placebo | | | Negative | |
Rodriguez, 2004 | metformin | placebo | | | - | |
Gambineri, 2004 | metformin | placebo | | | - | |
Hoeger, 2004 | metformin | placebo | | | - | |
James, 2005 | metformin | control | | | - | |
Stakos, 2005 | metformin | placebo | | | - | |
Vitale, 2005 | metformin | placebo | | | - | |
Orchard, 2005 | metformin | placebo | | | Suggesting | |
IDDP (Ramachandran), 2006 | lifestyle modification + metformin | control | | Risk of bias | Negative | |
Bridger, 2006 | metformin | placebo | | | - | |
Srinivasan, 2006 | metformin | placebo | | | - | |
Tang, 2006 | metformin | placebo | | | - | |
CANOE, 2010 | rosiglitazone and metformin | placebo | | Low risk of bias | Suggesting | NCT00116932 |
|
NAVIGATOR nateglinide, 2010 | nateglinide | placebo | | Low risk of bias | Negative | NCT00097786 |
|
Heymsfield, 2000 | orlistat | placebo | | Low risk of bias | Negative | |
XENDOS (Chiasson), 2002 | orlistat | placebo | | Risk of bias | Negative | |
|
DREAM ramipril, 2006 | ramipril | placebo | | Low risk of bias | Negative | NCT00095654 |
|
DREAM rosiglitazone, 2006 | rosiglitazone | placebo | | Low risk of bias | Suggesting | NCT00095654 |
|
TRIPOD (Buchanan), 2002 | troglitazone | placebo | | Exploratory | - | |
US DDP troglitazone (Knowler), 2005 | troglitazone | placebo | | Low risk of bias | - | |
|
NAVIGATOR valsartan, 2010 | valsartan | placebo | | Low risk of bias | Suggesting | NCT00097786 |
|
Voglibose Ph-3, 2009 | voglibose | placebo | | Low risk of bias | Suggesting | UMIN 000001109- |
|
|
GRACE - ORIGIN (glargine), 2012 | insulin glargine | placebo | | | - | |
|
US-DPP (metformin) (Knowler), 2002 | metformin | placebo | | Low risk of bias | Negative | |
CANOE, 2010 | rosiglitazone and metformin | placebo | | Low risk of bias | Suggesting | NCT00116932 |
|
NAVIGATOR nateglinide, 2010 | nateglinide | placebo | | Low risk of bias | Negative | NCT00097786 |
|
DREAM ramipril, 2006 | ramipril | placebo | | Low risk of bias | Negative | NCT00095654 |
|
DREAM rosiglitazone, 2006 | rosiglitazone | placebo | | Low risk of bias | Suggesting | NCT00095654 |
|
NAVIGATOR valsartan, 2010 | valsartan | placebo | | Low risk of bias | Suggesting | NCT00097786 |
|
Voglibose Ph-3, 2009 | voglibose | placebo | | Low risk of bias | Suggesting | UMIN 000001109- |
|
|
VISP (Toole), 2004 | high dose - folic acid, vit B12 and vit B6 | low dose - folic acid, vit B12 and vit B6 | | Low risk of bias | Negative | |
VITATOPS, 2010 | folic acid, vit B12 and vit B6 | placebo | | Low risk of bias | Suggesting | NCT00097669ÐX& |