new version V2017

Ramipril angiotensin-Converting Enzyme Inhibitors

Zabien - Tritace - Acovil - Carasel - Vesdil - Ramace - Delix - Altace - Triatec      

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TrialStudied treatmentControl treatmentpatientsROBResultNCT

acute myocardial infarction

AIRE, 1993ramiprilplacebo Low risk of bias -
Wagner, 2002ramiprilplacebo Exploratory -

atrial fibrillation

Brown ongoing ramiprilplacebo - NCT00141778

diabetes type 2

DIABHYCAR, 2004ramiprilplacebo Low risk of bias Negative
DREAM ramipril, 2006ramiprilplacebo Low risk of bias Negative NCT00095654
DREAM, 2008ramiprilplaceboNegative

diabetic kidney disease

DIABHYCAR, 2004ramiprilplacebo Low risk of bias Negative

heart failure

Swedberg, 1991ramiprilcontrolNegative
Maass-a, 1991ramiprilplaceboNegative
Gordon, 1991ramiprilplacebo Exploratory Suggesting
Maass-b, 1991ramiprilplacebo Exploratory Negative
Maass-c, 1991ramiprilplacebo Exploratory Negative
Lemarie, 1992ramiprilplacebo Exploratory Negative
AIRE, 1993ramiprilplacebo Low risk of bias -
Gundersen, 1994ramiprilplacebo Exploratory -

hypertension

AASK (ramipril vs amlodipine), 2002ramiprilamlodipineNegative
AASK (ramipril vs metoprolol), 2002ramiprilmetoprololNegative
Li et al, 2003ramiprilusual careNegative
ONTARGET/Tel+Ram, 2008Telmisartan + ramiprilRamipril Low risk of bias Negative

impaired fasting glucose

DREAM ramipril, 2006ramiprilplacebo Low risk of bias Negative NCT00095654

miscellaneous

ONTARGET (association vs ramipril), 2008telmisartan + ramiprilramiprilNegative NCT00153101
ONTARGET (association vs telmisartan), 2008telmisartan + ramipriltelmisartanSuggesting NCT00153101

patients at high risk for cardiovascular events

HOPE, 2000ramiprilplaceboSuggesting
ONTARGET (association vs ramipril), 2008telmisartan + ramiprilramiprilNegative NCT00153101
ONTARGET (association vs telmisartan), 2008telmisartan + ramipriltelmisartanSuggesting NCT00153101