angiotensin-Converting Enzyme Inhibitors
Trials Results

Benazepril - Captopril - Enalapril - Fosinopril - Lisinopril - Perindopril - Quinapril - Ramipril - Trandolapril - Various ACEI - Zofenopril

  • Group by...

TrialStudied treatmentControl treatmentpatientsROBResultNCT

acute myocardial infarction

captopril
Pfeffer, 1988captoprilplacebo Exploratory -
Sharpe, 1988captoprilplacebo Exploratory -
Mortarino, 1990captoprilplacebo Exploratory -
Sharpe, 1991captoprilplacebo Exploratory -
Nabel, 1991captoprilplacebo Exploratory -
SAVE, 1992captoprilplacebo Low risk of bias -
Hargreaves, 1992captoprilplacebo Exploratory -
Bussmann, 1992captoprilplacebo Exploratory -
Ray, 1993captoprilplacebo Exploratory -
Galcera, 1993captoprilplacebo Exploratory -
Di Pasquale, 1994captoprilplacebo Exploratory -
PRACTICAL (captopril), 1994captopril or enalaprilplacebo Exploratory -
Sogaard, 1994captoprilplacebo Exploratory -
CCS-1, 1995captoprilplacebo Low risk of bias -
ISIS-4, 1995captoprilplacebo Low risk of bias -
CATS, 1996captoprilplacebo Exploratory -
Di Pasquale, 1997captoprilplacebo Exploratory -
ECCE, 1997captoprilplacebo Exploratory -
French, 1999captoprilplacebo Exploratory -
enalapril
CONSENSUS 2, 1992enalaprilplacebo Low risk of bias -
Schulman, 1995enalaprilplacebo Exploratory -
fosinopril
FAMIS, 1998fosinoprilplacebo Exploratory -
irbesartan
GLOBAL ongoing irbesartancontrol Exploratory - NCT00125645
lisinopril
GISSI 3, 1994lisinoprilplacebo Risk of bias -
ramipril
AIRE, 1993ramiprilplacebo Low risk of bias -
Wagner, 2002ramiprilplacebo Exploratory -
trandolapril
TRACE, 1995trandolaprilplacebo Low risk of bias -
zofenopril
SMILE, 1995zofenoprilplacebo Low risk of bias Suggesting

heart failure

benazepril
McGany, 1991benazeprilcontrolNegative
Colfer, 1992benazeprilplacebo Exploratory Negative
captopril
CMRG, 1983captoprilplacebo Exploratory -
Magnani, 1986captoprilplacebo Exploratory -
packer, 1986captoprilenalapril Exploratory -
Bussmann, 1987captoprilplacebo Exploratory Negative
Captopril Digoxin Multicenter Research Group, 1988captoprilplacebo Low risk of bias Negative
Pfeffer, 1988captoprilplacebo Exploratory -
Sharpe, 1988captoprilplacebo Exploratory -
Magnani, 1990captoprilplacebo Exploratory -
Mortarino, 1990captoprilplacebo Exploratory -
Barabino, 1991captoprilplacebo Exploratory Suggesting
SAVE, 1992captoprilplacebo Low risk of bias -
Munich MHFT (Kleber), 1992captoprilplacebo Low risk of bias Negative
Sogaard, 1994captoprilplacebo Exploratory -
Cilazapril-Captopril Multi-centre Group (capt vs pbo), 1995captoprilplacebo Exploratory -
cilazapril
Drexler, 1989cilazaprilplacebo Exploratory Negative
Dosseger, 1993cilazaprilplacebo Exploratory -
Cilazapril-Captopril Multi-centre Group, 1995cilazaprilplacebo Exploratory -
Cilazapril-Captopril Multi-centre Group (cila vs capt), 1995cilazaprilcaptopril Exploratory -
enalapril
Sharpe, 1984enalaprilplacebo -
McGrath, 1985enalaprilplacebo -
Chrysant, 1985enalaprilplacebo Low risk of bias -
Cleland, 1985enalaprilplacebo Exploratory Negative
Enalapril CHF investigators, 1987enalaprilcontrolNegative
CONSENSUS, 1987enalaprilplacebo Low risk of bias Negative
SOLVD treatment, 1991enalaprilplacebo Low risk of bias Suggesting NCT00000516
V-HeFT II, 1991enalaprilhydralazine+ISDN Low risk of bias -
Rucinska-b (enalapril), 1991enalaprilcontrolNegative
Dickstein, 1991enalaprilplacebo Exploratory Negative
Rucinska-a (enalapril), 1991enalaprilcontrolNegative
SOLVD prevention, 1992enalaprilplacebo Low risk of bias - NCT00000516
CASSIS (enalapril), 1995enalaprilplacebo Exploratory -
NETWORK (2.5 bid vs 10 bid), 1998enalaprilenalapril Low risk of bias -
NETWORK (5 bid vs 10 bid), 1998enalaprilenalapril Low risk of bias -
fosinopril
Brown, 1995fosinoprilplacebo Exploratory -
FEST (Erhardt), 1996fosinoprilplacebo Exploratory -
lisinopril
Rucinska-c (lisinopril), 1000lisinoprilcontrolNegative
International Study Group (Lewis), 1989lisinoprilplacebo Exploratory -
Zwehl, 1990lisinoprilcontrolNegative
Giles, 1990lisinoprilcontrolNegative
Gilbert, 1993lisinoprilplaceboNegative
ATLAS, 1999lisinoprillisinopril Low risk of bias -
perindopril
Lechat, 1993perindoprilplaceboNegative
PEP CHF, 2006perindoprilplacebo Low risk of bias Negative
quinapril
Riegger, 1990placeboNegative
Northridge, 1991placebo Exploratory Negative
Rieger, 1991placebo Exploratory Negative
Quinapril Heart Failure Trial Investigators, 1993placebo Exploratory -
Uprichard-b, 1994controlNegative
Uprichard-a, 1994controlNegative
Nussberger, 1994placebo Exploratory -
Uprichard-c, 1994controlNegative
ramipril
Maass-b, 1991ramiprilplacebo Exploratory Negative
Maass-c, 1991ramiprilplacebo Exploratory Negative
Swedberg, 1991ramiprilcontrolNegative
Maass-a, 1991ramiprilplaceboNegative
Gordon, 1991ramiprilplacebo Exploratory Suggesting
Lemarie, 1992ramiprilplacebo Exploratory Negative
AIRE, 1993ramiprilplacebo Low risk of bias -
Gundersen, 1994ramiprilplacebo Exploratory -
trandolapril
TRACE, 1995trandolaprilplacebo Low risk of bias -
Hampton, 1998trandolaprilplacebo Exploratory -

patients at high risk for cardiovascular events

enalapril
CAMELOT (enalapril), 2004enalaprilplaceboNegative
perindopril
EUROPA, 2003perindoprilplaceboSuggesting
quinapril
QUIET, 2001quinaprilplaceboNegative
ramipril
HOPE, 2000ramiprilplaceboSuggesting
ONTARGET (association vs ramipril), 2008telmisartan + ramiprilramiprilNegative NCT00153101
ONTARGET (association vs telmisartan), 2008telmisartan + ramipriltelmisartanSuggesting NCT00153101
trandolapril
PEACE, 2004trandolaprilplaceboSuggestingNCT00000558



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