new version V2017

Captopril angiotensin-Converting Enzyme Inhibitors
Description Results

Lopirin - Capoten - SQ14225 - SQ 14225 - SQ-14225 - SQ14534 - SQ 14534 - SQ-14534      

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TrialStudied treatmentControl treatmentpatientsROBResultNCT

acute myocardial infarction

Sharpe, 1988captoprilplacebo Exploratory -
Pfeffer, 1988captoprilplacebo Exploratory -
Mortarino, 1990captoprilplacebo Exploratory -
Sharpe, 1991captoprilplacebo Exploratory -
Nabel, 1991captoprilplacebo Exploratory -
Hargreaves, 1992captoprilplacebo Exploratory -
Bussmann, 1992captoprilplacebo Exploratory -
SAVE, 1992captoprilplacebo Low risk of bias -
Galcera, 1993captoprilplacebo Exploratory -
Ray, 1993captoprilplacebo Exploratory -
Di Pasquale, 1994captoprilplacebo Exploratory -
PRACTICAL (captopril), 1994captopril or enalaprilplacebo Exploratory -
Sogaard, 1994captoprilplacebo Exploratory -
ISIS-4, 1995captoprilplacebo Low risk of bias -
CCS-1, 1995captoprilplacebo Low risk of bias -
CATS, 1996captoprilplacebo Exploratory -
Di Pasquale, 1997captoprilplacebo Exploratory -
ECCE, 1997captoprilplacebo Exploratory -
French, 1999captoprilplacebo Exploratory -

diabetes type 2

UKPDS 39, 1998captoprilatenolol Exploratory Negative
UKPDS 38, 1998captopril or atenololcontrol Exploratory Suggesting
CAPP (diabetic subgroup), 1999captoprildiuretic and/or beta-blockers Exploratory Suggesting

heart failure

CMRG, 1983captoprilplacebo Exploratory -
packer, 1986captoprilenalapril Exploratory -
Magnani, 1986captoprilplacebo Exploratory -
Bussmann, 1987captoprilplacebo Exploratory Negative
Pfeffer, 1988captoprilplacebo Exploratory -
Sharpe, 1988captoprilplacebo Exploratory -
Captopril Digoxin Multicenter Research Group, 1988captoprilplacebo Low risk of bias Negative
Mortarino, 1990captoprilplacebo Exploratory -
Magnani, 1990captoprilplacebo Exploratory -
Barabino, 1991captoprilplacebo Exploratory Suggesting
SAVE, 1992captoprilplacebo Low risk of bias -
Munich MHFT (Kleber), 1992captoprilplacebo Low risk of bias Negative
Sogaard, 1994captoprilplacebo Exploratory -
Cilazapril-Captopril Multi-centre Group (capt vs pbo), 1995captoprilplacebo Exploratory -

hypertension

UKPDS 39, 1998captoprilatenolol Exploratory Negative
UKPDS 38, 1998captopril or atenololcontrol Exploratory Suggesting
UKPDS-HDS, 1998captoprildiuretic or beta-blockerNegative
CAPP (diabetic subgroup), 1999captoprildiuretic and/or beta-blockers Exploratory Suggesting
CAPPP, 1999captoprildiuretic or beta-blocker Risk of bias Negative
VALIANT/Val+Cap, 2003Valsartan + captoprilCaptopril Low risk of bias Negative



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