Clinical trials of aspirin - TrialResults-center.org

Trial	Studied trt	Control trt	patients	ROB	Trial result	All cause death
Group by... in first in second in third	Synopsis Comparison Treatments Patients Characteristics Method Risk of bias References None Tools Indexation				Global trial result Main results All results All result tag NCT results	Numeric bar chart forest plot medians
acute coronary syndrome
ATACS-pilot, 1990	aspirin	control			negative
Huddinge, 1988	aspirin	control			negative
Frankfurt, 1976	aspirin	control			negative
VA-pilot	aspirin	placebo			negative
VA-main, 1983	aspirin	placebo		Low risk of bias	suggesting
RISC, 1990	aspirin	placebo		Low risk of bias	suggesting
ALDUSA-pilot	aspirin	placebo			negative
Théroux, 1988	aspirin	placebo		Low risk of bias	suggesting
Dutch-aspirin, 1990	aspirin	placebo		Low risk of bias	negative
ISIS-pilot, 1987	aspirin	placebo		Low risk of bias	negative
ISIS-2, 1988	aspirin	placebo		Low risk of bias	suggesting
APRICOT, 1993	aspirin	placebo		Low risk of bias	suggesting
Canadian (Aspirin vs PBO), 1985	aspirin	placebo		Low risk of bias	-
Canadian (Aspirin + sulfinpyrazone), 1985	aspirin + sulfinpyrazone	placebo		Low risk of bias	negative
acute myocardial infarction
Huddinge, 1988	aspirin	control			negative
Frankfurt, 1976	aspirin	control			negative
Dutch-aspirin, 1990	aspirin	placebo		Low risk of bias	negative
ISIS-pilot, 1987	aspirin	placebo		Low risk of bias	negative
ISIS-2, 1988	aspirin	placebo		Low risk of bias	suggesting
APRICOT, 1993	aspirin	placebo		Low risk of bias	suggesting
atrial fibrillation
LASAF(aspirin vs no treatment), 1999	aspirin	control			-
AFASAK (aspirin vs placebo), 1989	aspirin	placebo		Low risk of bias	negative
SPAF (aspirin,warfarin ineligible arm), 1991	aspirin	placebo	ineligible for VKA	Low risk of bias	negative
EAFT, 1993	aspirin	placebo		Low risk of bias	negative
SPAF (aspirin , warfarin eligible arm), 1991	aspirin	placebo		Low risk of bias	suggesting
FFAACS , 2001	aspirin	placebo (on top fluidione)		Low risk of bias	negative
PATAF (vs coumadin low dose), 1999	aspirin	coumadin low dose		Risk of bias	negative
PATAF (vs coumadin standard dose), 1999	aspirin	coumadin standard dose		Risk of bias	negative
AFASAK II (aspirin vs warfarin low dose), 1998	aspirin	warfarin low dose		Risk of bias	negative
SPAF II (aspirin vs warfarin standard dose, age<75), 1994	aspirin	warfarin standard dose		Risk of bias	negative
AFASAK II (aspirin vs warfarin standard dose), 1998	aspirin	warfarin standard dose		Risk of bias	negative
SPAF II (aspirin vs warfarin standard dose, age>75), 1994	aspirin	warfarin standard dose		Risk of bias	negative
AFASAK (aspirin vs warfarin standard dose), 1989	aspirin	warfarin standard dose		Risk of bias	negative
CABG surgery
McEnany, 1982	aspirin	placebo		Low risk of bias	negative
Lorenz, 1984	aspirin	placebo		Low risk of bias	negative
GESIC (aspirin), 1990	aspirin	placebo		Low risk of bias	negative
Sydney, 1991	aspirin	placebo		Low risk of bias	-
Hockings, 1993	aspirin	placebo		Low risk of bias	-
cardiovascular prevention
British Doctor’s Trial, 1988	aspirin	no treatment	primary prevention	Risk of bias	negative
Primary Prevention Project, 2001	aspirin	no treatment	primary prevention	Risk of bias	negative
JPAD, 2008 NCT	aspirin	no treatment		Risk of bias	suggesting
PPP (diabetics sub group), 2003	aspirin	no treatment		Exploratory	negative
CDPA, 1976	aspirin	placebo		Low risk of bias	negative
Cardiff I, 1974	aspirin	placebo		Low risk of bias	negative
Cardiff II, 1979	aspirin	placebo		Low risk of bias	negative
Vogel, 1979	aspirin	placebo		Low risk of bias	suggesting
AMIS, 1980 NCT	aspirin	placebo		Low risk of bias	suggesting
GAMIS, 1980	aspirin	placebo		Low risk of bias	negative
PARIS, 1980	aspirin	placebo		Low risk of bias	negative
JAMIS, 1999	aspirin	placebo			suggesting
Schoop, 1983	aspirin	placebo		Low risk of bias	-
Hess, 1985	aspirin	placebo			-
Munich A, 1975	aspirin	placebo		Low risk of bias	-
Munich B, 1975	aspirin	placebo		Low risk of bias	-
Physicians Health Study, 1989 NCT	aspirin	placebo	primary prevention	Low risk of bias	suggesting
Thrombosis Prevention Trial, 1998 NCT	aspirin	placebo	primary prevention	Low risk of bias	suggesting
HOT, 1998	aspirin	placebo	primary prevention	Low risk of bias	suggesting
Women’s Health Study, 2005	aspirin	placebo	primary prevention	Low risk of bias	suggesting
SAPAT, 1992	aspirin	placebo		Low risk of bias	suggesting
POPADAD aspirin, 2008	aspirin	placebo		Low risk of bias	negative
DAMAD, 1989	aspirin	placebo		Low risk of bias	negative
ETDRS, 1992	aspirin	placebo		Low risk of bias	suggesting
CLIPS, 2007	aspirin	placebo		Low risk of bias	suggesting
AAA, 2009	aspirin	placebo	secondary prevention	Low risk of bias	negative
PHS (diabetics sub group), 1989	aspirin	placebo		Low risk of bias	suggesting
WHS (diabetics sub group), 2005	aspirin	placebo		Low risk of bias	suggesting
ASPREE, 2018 NCT	aspirin	placebo			-
ASCEND, 2018 NCT	aspirin	placebo			suggesting
coronary artery disease
CDPA, 1976	aspirin	placebo		Low risk of bias	negative
Cardiff I, 1974	aspirin	placebo		Low risk of bias	negative
Cardiff II, 1979	aspirin	placebo		Low risk of bias	negative
Vogel, 1979	aspirin	placebo		Low risk of bias	suggesting
AMIS, 1980 NCT	aspirin	placebo		Low risk of bias	suggesting
GAMIS, 1980	aspirin	placebo		Low risk of bias	negative
PARIS, 1980	aspirin	placebo		Low risk of bias	negative
JAMIS, 1999	aspirin	placebo			suggesting
SAPAT, 1992	aspirin	placebo		Low risk of bias	suggesting
diabetes type 2
JPAD, 2008 NCT	aspirin	no treatment		Risk of bias	suggesting
PPP (diabetics sub group), 2003	aspirin	no treatment		Exploratory	negative
POPADAD aspirin, 2008	aspirin	placebo		Low risk of bias	negative
DAMAD, 1989	aspirin	placebo		Low risk of bias	negative
ETDRS, 1992	aspirin	placebo		Low risk of bias	suggesting
PHS (diabetics sub group), 1989	aspirin	placebo		Low risk of bias	suggesting
WHS (diabetics sub group), 2005	aspirin	placebo		Low risk of bias	suggesting
heart failure
WASH (aspirin), 2004	aspirin	no treatment			negative
Barzizza (ASA), 1993	aspirin	placebo		Exploratory	-
hypertension
HOT, 1998	aspirin	placebo	primary prevention	Low risk of bias	suggesting
percutaneous coronary intervention
Taylor (Perth), 1991	aspirin	placebo		Low risk of bias	negative
M-HEART II (aspirin), 1995	aspirin	placebo		Low risk of bias	negative
peripheral vascular diseases
Lassila R, 1991	aspirin	contrôle			-
Schoop, 1983	aspirin	placebo		Low risk of bias	-
Hess, 1985	aspirin	placebo			-
Munich A, 1975	aspirin	placebo		Low risk of bias	-
Munich B, 1975	aspirin	placebo		Low risk of bias	-
CLIPS, 2007	aspirin	placebo		Low risk of bias	suggesting
BOA, 2000	aspirin				-
post myocardial infarction
CDPA, 1976	aspirin	placebo		Low risk of bias	negative
Cardiff I, 1974	aspirin	placebo		Low risk of bias	negative
Cardiff II, 1979	aspirin	placebo		Low risk of bias	negative
Vogel, 1979	aspirin	placebo		Low risk of bias	suggesting
AMIS, 1980 NCT	aspirin	placebo		Low risk of bias	suggesting
GAMIS, 1980	aspirin	placebo		Low risk of bias	negative
PARIS, 1980	aspirin	placebo		Low risk of bias	negative
JAMIS, 1999	aspirin	placebo			suggesting
post stroke
Canadian study (CCSG), 1978	aspirin	placebo		Low risk of bias	negative
Swedish study , 1987	aspirin	placebo			negative
UK-TIA low dose , 1988	aspirin	placebo			negative
UK-TIA high dose , 1988	aspirin	placebo			suggesting
SALT , 1991	aspirin	placebo			negative
Reuther , 1976	aspirin	placebo			negative
AITA, 1975	aspirin	placebo			negative
DCS, 1980	aspirin	placebo			negative
AICLA, 1981	aspirin	placebo			negative
Lindblad , 1991	aspirin	placebo			suggesting
Danish low-dose, 1986	aspirin	placebo			negative
ESPS 2 , 1996	aspirin	placebo			suggesting
stable angina
SAPAT, 1992	aspirin	placebo		Low risk of bias	suggesting
thrombosis prevention
Lieberman (A), 1994	IPC + aspirin	aspirin			negative
Hull (+asp), 1979	IPC + aspirin	aspirin			negative
Hull 2 (+asp), 1979	IPC + aspirin	aspirin			-
Clagett, 1975	aspirin	control		Risk of bias	-
Zekert VI, 1982	aspirin	control		Risk of bias	-
Gelfer, 2006	CECT + aspirin	LMWH			-
Pasteyer, 1977	Aspirin	no treatment		Exploratory	negative
Rocha, 1986	Aspirin	no treatment		Exploratory	suggesting
PEP hip-fracture, 2000	aspirin	placebo		Low risk of bias	suggesting
MRC, 1972	aspirin	placebo		Low risk of bias	negative
Loew DVT, 1974	aspirin	placebo		Low risk of bias	-
Erfurt-A, 1979	aspirin	placebo		Low risk of bias	-
Zekert V, 1980	aspirin	placebo		Low risk of bias	-
Vinazzer I, 1980	aspirin	placebo		Low risk of bias	-
Vinazzer II, 1977	aspirin	placebo		Low risk of bias	-
PEP elective arthroplasty, 2000	aspirin	placebo		Low risk of bias	-
Stockholm-I, 1975	Aspirin	placebo		Exploratory	negative
Harris-I, 1977	Aspirin	placebo		Low risk of bias	suggesting
McKenna-I, 1980	Aspirin	placebo		Exploratory	suggesting
Sautter, 1983	Aspirin	placebo		Exploratory	suggesting
McBride, 1983	Aspirin	placebo		Exploratory	negative
Zekert-I , 1974	Aspirin	placebo		Exploratory	suggesting
Powers , 1976	Aspirin	placebo		Exploratory	suggesting
Erfurt-B , 1979	Aspirin	placebo		Exploratory	negative
venous thrombosis
WARFASA, 2012 NCT	aspirin	discontinuation		Low risk of bias	suggesting
ASPIRE, 2012	aspirin	discontinuation			suggesting

Aspirin antiplatelets drug systematic review meta-analysis network meta-analysis

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Aspirin antiplatelets drug
systematic review meta-analysis network meta-analysis