Aliskiren renin inhibitor  

SPP100 - Tekturna - CGP-060536B - CGP060536B - CGP 060536B      

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Trial Studied trt Control trt patientstagsROB Trial resultcardiovascular eventsany adverse event

heart failure  

ASTRONAUT, 2013    NCTAliskirenplaceboLow risk of bias -

hypertension  

ACCELERATE, 2011    NCTaliskiren amlodipine -
AVOID, 2008      NCTaliskirenplaceboLow risk of bias negative-1%
Schmieder (vs HCTZ), 2009     aliskirenhydrochlorothiazideLow risk of bias negative6%
ALLAY, 2009      NCTaliskirenlosartanExploratory negative10%
Andersen, 2008     aliskirenramiprilLow risk of bias -