renin inhibitor

systematic review meta-analysis network meta-analysis

Select heart failurehypertension acute decompensated heart failureAll type of patientDiabetic patients       direct renin inhibitor direct renin inhibitor aliskiren vs placebo or controlvs angiotensin receptor blockervs angiotensin-converting enzyme inhibitorsvs diuretics      

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Group by Group by... nothing pathology treatment patient comparator classe classe comparator mechanism clinical condition MA  in first nothing pathology treatment patient comparator classe classe comparator mechanism clinical condition  in second nothing pathology treatment patient comparator classe classe comparator mechanism clinical condition  in third	Description Synopsis Comparison Treatments Patients Characteristics Method Risk of bias References None Tools Indexation					Results Global trial result Main results All results All result tag NCT results	any adverse event (4)Serious adverse event (4)Adverse events leading to treatment discontinuation (4)All cause death (3) Options Numeric bar chart forest plot medians
Trial	Studied trt	Control trt	patients	tags	ROB	Trial result	any adverse event	Serious adverse event
heart failure
aliskiren
ASTRONAUT, 2013    NCT	Aliskiren	placebo			Low risk of bias	-
hypertension
aliskiren
AVOID, 2008      NCT	aliskiren	placebo			Low risk of bias	negative
Schmieder (vs HCTZ), 2009	aliskiren	hydrochlorothiazide			Low risk of bias	negative
ALLAY, 2009      NCT	aliskiren	losartan			Exploratory	negative
Andersen, 2008	aliskiren	ramipril			Low risk of bias	-