new version V2017

Spironolactone aldosterone blockade

spiro von ct - Spiro L.U.T. - Practon - NovoSpiroton - Novo Spiroton - Novo-Spiroton - Jenaspiron - Frumikal - Flumach - Espironolactona Mundogen - Espironolactona Alter - duraspiron - Aquareduct - Aldactone A - Aldactone - Verospiron - Spirospare - Spironone - Spirono Isis - Spirono-Isis - Spirolang - Spirogamma - Spirobeta - Spiractin - Verospirone - Veroshpiron      

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TrialStudied treatmentControl treatmentpatientsROBResultNCT

heart failure

Mauersberger, 1985spironolactone+furosemidespironolactone+butizide Exploratory -
Dalhstrom, 1986furosemide + spironolactoneprenalterol Exploratory Negative
Han, 1994spironolactone+captoprilcaptopril Exploratory -
Barr, 1995spironolactoneplacebo Exploratory -
MacFadyen, 1997spironolactoneplacebo Exploratory -
RALES, 1998spironolactoneplacebo Risk of bias Suggesting
Ramires, 2000spironolactonecontrol Exploratory -
Bednarz, 2000aldactonefurosemide Exploratory -
Farquharson, 2000spironolactoneplacebo Exploratory -
Yee, 2001spironolactoneplacebo -
Tsutamoto, 2001spironolactoneplacebo Exploratory -
Cicoira, 2002spironolactonecontrol Exploratory -
Cicoira, 2004spironolactonecontrol -
Mottram, 2004spironolactoneplacebo Exploratory -
Macdonald, 2004spironolactoneplacebo Exploratory -
Agostoni, 2005spironolactoneplacebo Exploratory -
PIE II ongoing spironolactoneplacebo - NCT00123955
Nouvel essai ongoing spironolactonespironolactone Exploratory - NCT00125437