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new version V2017
Rolofylline
diuretics
Description
Results
MK-7418 - MK7418 - MK 7418 - KW-3902 - KW 3902 - rolofylline
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pathology
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pathology
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patient
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in second
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pathology
treatment
patient
comparator
classe
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mechanism
in third
acute heart failure
heart failure
Synopsis
Synopsis
Results
Treatments
Patients_
Method
References
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All cause death
Adverse events
Cardiovascular death
Death from any cause or hospitalization for any reason
hospitalisation for heart failure
Sudden death
serious hyperkalemia
death from cardiovascular causes or hospitalization for cardiovascular causes
hospitalisation for cardiovascular causes
Adverse events leading to treatment discontinuation
NYHA class improvement
exacerbation of heart failure
Hospitalization for any reason
Death from any cause or hospitalization for heart failure
NYHA change
LV ejection fraction
exercise capacity
death from cardiovascular causes or hospitalization for heart failure
pdf
Trial
Studied treatment
Control treatment
patients
ROB
Result
NCT
acute heart failure
PROTECT, 2010
rolofylline
placebo
Low risk of bias
Negative
NCT00328692
heart failure
PROTECT-1
rolofylline
placebo
-
NCT00328692
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