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cardiac arrest
Description
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antiarrythmic drugs
compression-only CPR
fibrinolysis
modified resuscitation protocol
omega-3 fatty acids
Public Access Defibrillation
vasopressin
amiodarone
fish oil
t-pa
tenecteplase
Synopsis
Synopsis
Results
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Patients_
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All cause death
Coronary event
Cancer
ischemic stroke
intracranial hemorrhage
stroke (fatal and non fatal)
myocardial infarction (fatal and non fatal)
Sudden death
cardiovascular events
Survival to hospital discharge
Return of spontaneous circulation
survival to hospital admission
Failure of return of spontaneous circulation
Death before hospital admission
Death within 24 hours
Death before hospital discharge
survivors of definite out of hospital cardiac arrest
implantable cardioverter defibrillator discharge
favorable neurologic outcome at discharge
long-term survival
Trial
Studied treatment
Control treatment
patients
ROB
Result
NCT
antiarrythmic drugs
amiodarone
ARREST, 1999
amiodarone
placebo
Suggesting
ALIVE, 2002
amiodarone
lidocaine
Suggesting
fibrinolysis
t-pa
Abu-Laban, 2002
t-PA
placebo
Exploratory
Negative
tenecteplase
TICA, 2004
tenecteplase
placebo
Exploratory
Negative
TROICA, 2008
tenecteplase
placebo
Low risk of bias
Negative
NCT00157261
omega-3 fatty acids
fish oil
Leaf, 2005
fish oil
placebo
Suggesting
Raitt , 2006
fish oil
placebo
Negative
NCT00004558
SOFA , 2006
fish oil
placebo
Low risk of bias
Negative
NCT00110838
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