new version V2017

Ticagrelor antiplatelets drug

AZD-6140 - AZD6140 - AZD 6140 - Brilinta - Brilique      

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TrialStudied treatmentControl treatmentpatientsROBResultNCT

acute coronary syndrome

DISPERSE-2 (90mg), 2007ticagrelorclopidogrel Exploratory Negative
PLATO, 2009ticagrelorclopidogrel Low risk of bias SuggestingNCT00391872

cardiovascular prevention

PEGASUS 60mg, 2015ticagrelorplacebo (on top aspirin)secondary prevention Low risk of bias Suggesting NCT01225562
PEGASUS 90mg, 2015ticagrelorplacebo (on top aspirin)secondary preventionSuggesting NCT01225562

post myocardial infarction

PEGASUS 60mg, 2015ticagrelorplacebo (on top aspirin)secondary prevention Low risk of bias Suggesting NCT01225562
PEGASUS 90mg, 2015ticagrelorplacebo (on top aspirin)secondary preventionSuggesting NCT01225562