new version V2017

Rosuvastatin cholesterol lowering intervention

Crestor      

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TrialStudied treatmentControl treatmentpatientsROBResultNCT

aortic stenosis

ASTRONOMER, 2010rosuvastatinplaceboaortic stenosis - ISRCTN 32424163

cardiovascular prevention

METEOR, 2007rosuvastatinplacebodiabetic Exploratory NegativeNCT00225589
CORONA, 2007rosuvastatinplaceboheart failure Low risk of bias NegativeNCT00206310
Krum, 2007rosuvastatinplaceboheart failure Exploratory Negative
JUPITER, 2008rosuvastatinplaceboprimary prevention Low risk of bias Conclusive NCT00239681
GISSI-HF rosuvastatine, 2008rosuvastatinplaceboheart failure Low risk of bias Negative NCT00336336
JUPITER (women subgroup) , 2008Rosuvastatinplacebowomen Exploratory Suggesting
AURORA, 2009rosuvastatinplacebo Low risk of bias Negative
JUPITER (elderly sub group), 2009rosuvastatinplaceboelderly Exploratory Suggesting
ASTRONOMER, 2010rosuvastatinplaceboaortic stenosis - ISRCTN 32424163
HOPE 3, 2016rosuvastatinplaceboprimary prevention Low risk of bias ConclusiveNCT00468923
ASTEROID ongoing Rosuvastatincontrol -

heart failure

CORONA, 2007rosuvastatinplaceboheart failure Low risk of bias NegativeNCT00206310
Krum, 2007rosuvastatinplaceboheart failure Exploratory Negative
GISSI-HF rosuvastatine, 2008rosuvastatinplaceboheart failure Low risk of bias Negative NCT00336336

venous thrombosis

VanGogh extension, 2007idraparinuxdiscontinuationSuggesting NCT00071279