Telmisartan angiotensin-receptor blockers

Pritor - BIBR-277 - BIBR 277 - Micardis - telmisartan



Trial Studied treatment Control Patients Size Study type Results NCT

Heart failure - angiotensin-receptor blockers in all type of patients - angiotensin-receptor blockers in patients already receiving ACE inhibitor

REPLACE, 2001telmisartanenalapril378 (301/77) Exploratory

Hypertension - angiotensin-receptor blockers in all diseases requiring ACEi (HF, CHD, HT,...) - anti hypertensive agents in all type of patient - anti hypertensive agents in post stroke - anti hypertensive agents in patients undergoing dialysis

DETAIL, 2004TelmisartanEnalapril250 (120/130) Confirmatory
PROPHESS, 2008telmisartanplacebo20332 (10146/10186) Confirmatory NCT00153062
Cice et al, 2006telmisartanplacebo303 (151/152)
ONTARGET/Tel, 2008TelmisartanRamipril17118 (8542/8576) Confirmatory

Miscellaneous - angiotensin-receptor blockers in all type of patients

TRANSCEND, 2008telmisartanplacebo5926 (2954/2972) Confirmatory NCT00153101
PROPHESS, 2008telmisartanplacebo20332 (10146/10186) Confirmatory NCT00153062
ONTARGET (telmisartan alone), 2008telmisartanramipril17118 (8542/8576) Confirmatory NCT00153101

Patients at high risk for cardiovascular events - angiotensin-receptor blockers in all type of patients - inhibition of the renin-angiotensin system (ACEI or ARB) in all type of patients - angiotensin-receptor blockers in patients intolerant to ACE inhibitors

TRANSCEND, 2008telmisartanplacebo5926 (2954/2972) Confirmatory NCT00153101
PROPHESS, 2008telmisartanplacebo20332 (10146/10186) Confirmatory NCT00153062
ONTARGET (telmisartan alone), 2008telmisartanramipril17118 (8542/8576) Confirmatory NCT00153101

Post stroke - anti hypertensive agents in all type of patients

PROFESS, 2008telmisartanplaceboNA