tivozanib vs sorafenib | No demonstrated result suggested progression or death (progression free survival PFS) by 20% (not demonstrated) | Endpoint | TE [95% CI] | p val | I2 | n | k | trials |
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death (overall survival) | 1.25 [0.95 1.63] | p=1.00 | 0 | 517 | 1 | TIVO-1, | progression or death (progression free survival PFS) | 0.80 [0.64 0.99] | p=0.04 | 0 | 517 | 1 | TIVO-1, | TE: treatment effect; CI: confidence interval; k: nulmber of trials; n: total number of patients |