All type of patients: 1 trials - HORIZON
| temsirolimus + letrozole vs letrozole alone | No demonstrated result |
All type of patients: 2 trials - ARCC (Hudes) temsirolimus alone - INTORSECT
| temsirolimus vs interferon alpha | No demonstrated result suggested death (overall survival) by 27% (not demonstrated) | |
| temsirolimus vs sorafenib | No demonstrated result suggested death (overall survival) by 31% (not demonstrated) |
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