| carotid artery stenting vs surgery | No demonstrated result suggested Stroke within 30 days by 55% (not demonstrated) suggested Cranial neuropathy within 30 days by 91% (not demonstrated) suggested Death or neurological complication within 30 days by 37% (not demonstrated) suggested Death or stroke or myocardial infarction by 35% (not demonstrated) suggested Stroke during follow up by 61% (not demonstrated) suggested long term restenosis by 182% (not demonstrated) | | Endpoint | TE [95% CI] | p val | I2 | n | k | trials |
|---|
| Death or any stroke within 30 days | 1.29 [0.97 1.71] | p=1.00 | 0 | 3132 | 10 | Leicester (Naylor),WALLSTENT (Alberts),CAVATAS-CEA,Kentucky A (Brooks),SPACE,EVA-3S (Mas),BACASS (Hoffman),Kentucky B (Brooks),SAPPHIRE (yadav),TESCAS-C (Ling), | | Death or disabling stroke within 30 days | 1.16 [0.79 1.71] | p=1.00 | 0 | 2774 | 8 | Leicester (Naylor),CAVATAS-CEA,Kentucky A (Brooks),SPACE,EVA-3S (Mas),BACASS (Hoffman),Kentucky B (Brooks),SAPPHIRE (yadav), | | Death within 30 days | 0.85 [0.43 1.66] | p=1.00 | 0 | 2839 | 7 | CAVATAS-CEA,Kentucky A (Brooks),SPACE,EVA-3S (Mas),BACASS (Hoffman),SAPPHIRE (yadav),TESCAS-C (Ling), | | Stroke within 30 days | 1.55 [1.24 1.94] | p=0.04 | 0 | 6784 | 7 | CAVATAS-CEA,SPACE,EVA-3S (Mas),BACASS (Hoffman),SAPPHIRE (yadav),CREST,ICSS, | | Cranial neuropathy within 30 days | 0.09 [0.04 0.20] | p=0.04 | 0 | 3888 | 5 | CAVATAS-CEA,EVA-3S (Mas),BACASS (Hoffman),SAPPHIRE (yadav),CREST, | | Death or neurological complication within 30 days | 0.63 [0.45 0.89] | p=0.04 | 0 | 1386 | 4 | CAVATAS-CEA,EVA-3S (Mas),BACASS (Hoffman),SAPPHIRE (yadav), | | Death or stroke or myocardial infarction | 1.35 [1.02 1.77] | p=0.04 | 0 | 3099 | 5 | CAVATAS-CEA,EVA-3S (Mas),BACASS (Hoffman),SAPPHIRE (yadav),ICSS, | | Death or any stroke (during follow up) | 1.15 [0.86 1.54] | p=1.00 | 0 | 3483 | 7 | WALLSTENT (Alberts),CAVATAS-CEA,EVA-3S (Mas),BACASS (Hoffman),SAPPHIRE (yadav),TESCAS-C (Ling),ICSS, | | Death during follow up | 1.05 [0.62 1.79] | p=1.00 | 0 | 2593 | 4 | EVA-3S (Mas),BACASS (Hoffman),SAPPHIRE (yadav),ICSS, | | Stroke during follow up | 1.61 [1.11 2.33] | p=0.04 | 0 | 2593 | 4 | EVA-3S (Mas),BACASS (Hoffman),SAPPHIRE (yadav),ICSS, | | long term restenosis | 2.82 [1.62 4.93] | p=0.04 | 0 | 413 | 1 | CAVATAS-CEA, | | long term stroke | 1.23 [0.72 2.12] | p=1.00 | 0 | 504 | 1 | CAVATAS-CEA, | | long term fatal stroke | 2.52 [0.96 6.60] | p=1.00 | 0 | 504 | 1 | CAVATAS-CEA, | | non-perioperative ipsilateral stroke | 1.07 [0.72 1.60] | p=1.00 | 0 | 4604 | 4 | CAVATAS-CEA,SPACE,EVA-3S (Mas),CREST, |
TE: treatment effect; CI: confidence interval; k: nulmber of trials; n: total number of patients |
