Aspirin clinical trials antiplatelets drug

Acute coronary syndrome

ACS (excluding AMI):  8 trials  - ATACS-pilot - RISC - Théroux - Canadian (Aspirin + sulfinpyrazone) - Canadian (Aspirin vs PBO) - VA-main - ALDUSA-pilot - VA-pilot

All type of patients:  8 trials  - ATACS-pilot - RISC - Théroux - Canadian (Aspirin + sulfinpyrazone) - Canadian (Aspirin vs PBO) - VA-main - ALDUSA-pilot - VA-pilot

STEMI patients:  6 trials  - APRICOT - Dutch-aspirin - Huddinge - ISIS-2 - ISIS-pilot - Frankfurt

Acute myocardial infarction

6 trials  - APRICOT - Dutch-aspirin - Huddinge - ISIS-2 - ISIS-pilot - Frankfurt

Atrial fibrillation

Patients ineligible for warfarin:  1 trials  - SPAF (aspirin,warfarin ineligible arm)

Primary prevention of thromboembolic events:  12 trials  - LASAF(aspirin vs no treatment) - PATAF (vs coumadin low dose) - PATAF (vs coumadin standard dose) - AFASAK II (aspirin vs warfarin low dose) - AFASAK II (aspirin vs warfarin standard dose) - SPAF II (aspirin vs warfarin standard dose, age<75) - SPAF II (aspirin vs warfarin standard dose, age>75) - SPAF (aspirin , warfarin eligible arm) - SPAF (aspirin,warfarin ineligible arm) - AFASAK (aspirin vs placebo) - AFASAK (aspirin vs warfarin standard dose) - BAFTA (aspirin vs warfarin standard dose)

Secondary prevention of thromboembolic events:  2 trials  - FFAACS - EAFT

CABG surgery

5 trials  - Hockings - Sydney - GESIC (aspirin) - Lorenz - McEnany

Cardiovascular prevention

All type of patients:  10 trials  - ASCEND - ASPREE - AAA - Women’s Health Study - Primary Prevention Project - HOT - Thrombosis Prevention Trial - Physicians Health Study - British Doctor’s Trial - JPPP

Diabetic patients :  9 trials  - JPAD - POPADAD aspirin - WHS (diabetics sub group) - PPP (diabetics sub group) - ETDRS - DAMAD - PHS (diabetics sub group) - ACCEPT-D - ASCEND (aspirin)

Patients without established disease:  12 trials  - ASCEND - ASPREE - AAA - JPAD - POPADAD aspirin - Women’s Health Study - Primary Prevention Project - HOT - Thrombosis Prevention Trial - Physicians Health Study - British Doctor’s Trial - JPPP

Primary prevention:  10 trials  - ASCEND - ASPREE - AAA - Women’s Health Study - Primary Prevention Project - HOT - Thrombosis Prevention Trial - Physicians Health Study - British Doctor’s Trial - JPPP

Secondary prevention in patients with CAD:  9 trials  - JAMIS - SAPAT - AMIS - GAMIS - PARIS - Cardiff II - Vogel - CDPA - Cardiff I

Secondary prevention in patients with intermittent claudication:  5 trials  - CLIPS - Hess - Schoop - Munich A - Munich B

Coronary artery disease

9 trials  - JAMIS - SAPAT - AMIS - GAMIS - PARIS - Cardiff II - Vogel - CDPA - Cardiff I

Diabetes type 2

All type of patients:  9 trials  - JPAD - POPADAD aspirin - WHS (diabetics sub group) - PPP (diabetics sub group) - ETDRS - DAMAD - PHS (diabetics sub group) - ACCEPT-D - ASCEND (aspirin)

Patients without cardiovascular disease:  9 trials  - JPAD - POPADAD aspirin - WHS (diabetics sub group) - PPP (diabetics sub group) - ETDRS - DAMAD - PHS (diabetics sub group) - ACCEPT-D - ASCEND (aspirin)

Heart failure

2 trials  - WASH (aspirin) - Barzizza (ASA)

Hypertension

1 trials  - HOT

Percutaneous coronary intervention

2 trials  - M-HEART II (aspirin) - Taylor (Perth)

Peripheral vascular diseases

After revascularisation:  2 trials  - BOA - Lassila R

All type of patient:  5 trials  - CLIPS - Hess - Schoop - Munich A - Munich B

All type of patients:  1 trials  - CLIPS

Post myocardial infarction

All type of patient:  8 trials  - JAMIS - AMIS - GAMIS - PARIS - Cardiff II - Vogel - CDPA - Cardiff I

All type of patients:  8 trials  - JAMIS - AMIS - GAMIS - PARIS - Cardiff II - Vogel - CDPA - Cardiff I

Post stroke

12 trials  - ESPS 2 - Lindblad - SALT - UK-TIA high dose - UK-TIA low dose - Swedish study - Danish low-dose - AICLA - DCS - Canadian study (CCSG) - Reuther - AITA

Stable angina

1 trials  - SAPAT

Thrombosis prevention

All type of patients:  17 trials  - PEP elective arthroplasty - PEP hip-fracture - Rocha - McBride - Sautter - Zekert VI - McKenna-I - Vinazzer I - Zekert V - Erfurt-A - Harris-I - Pasteyer - Vinazzer II - Clagett - Stockholm-I - Loew DVT - MRC

Elective hip replacement:  4 trials  - Rocha - Sautter - Harris-I - Stockholm-I

Elective major knee surgery :  1 trials  - McKenna-I

Elective orthopedic surgery:  7 trials  - Rocha - McBride - Sautter - McKenna-I - Harris-I - Pasteyer - Stockholm-I

General surgery:  10 trials  - PEP elective arthroplasty - PEP hip-fracture - Zekert VI - Vinazzer I - Zekert V - Erfurt-A - Vinazzer II - Clagett - Loew DVT - MRC

Hip Fracture:  1 trials  - PEP hip-fracture

Orthopedic surgery:  11 trials  - PEP hip-fracture - Rocha - McBride - Sautter - McKenna-I - Erfurt-B - Harris-I - Pasteyer - Powers - Stockholm-I - Zekert-I

Venous thrombosis

2 trials  - ASPIRE - WARFASA