percutaneous coronary intervention | pexelizumab | not classified | versus placebo or control No demonstrated result for efficacy | 1 trial | meta-analysis | | Trial | control | p<0.05 | harm | NS |
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APEX-AMI, 2007 | pexelizumab vs placebo | | | All cause death 1.04 [0.80; 1.33] severe bleeding 1.01 [0.54; 1.90] Serious infection 0.90 [0.65; 1.25] |
Trial | Treatments | Patients | Method |
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APEX-AMI, 2007 | pexelizumab given as a 2-mg/kg intravenous bolus prior to PCI followed by 0.05-mg/kg per hour infusion over the subsequent 24 hours (n=2860) vs. placebo (n=2885) | primary angioplasty fo high risk STEMI | double blind Parallel groups Sample size: 2860/2885 Primary endpoint: all cause mortality FU duration: 30 days |
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