Spironolactone aldosterone blockade

spiro von ct - Spiro L.U.T. - Practon - NovoSpiroton - Novo Spiroton - Novo-Spiroton - Jenaspiron - Frumikal - Flumach - Espironolactona Mundogen - Espironolactona Alter - duraspiron - Aquareduct - Aldactone A - Aldactone - Verospiron - Spirospare - Spironone - Spirono Isis - Spirono-Isis - Spirolang - Spirogamma - Spirobeta - Spiractin - Verospirone - Veroshpiron      

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pathology Demonstrated benefit and harm k      
heart failure

versus placebo or control

No demonstrated result for efficacy

spironolactone inferior to placebo in terms of Discontinuation because of adverse event in RALES, 1998

spironolactone inferior to placebo in terms of NYHA functional class improvement in RALES, 1998

12 trialsmeta-analysis
heart failure

versus active treatment

No demonstrated result for efficacy

4 trialsmeta-analysis