CHIR-258 - CHIR258 - CHIR 258 - dovitinib - TKI-258 - TKI258 - TKI 258
versus
No demonstrated result for efficacy
PFS 0.86 [0.72; 1.03]
dovitinib (500 mg orally according to a 5-days-on and 2-days-off schedule) (n=284)
vs.
sorafenib (400 mg orally twice daily) (n=286)
open-label
Sample size: 284/286
Primary endpoint:
FU duration: