acute myocardial infarction | versus placebo or control No demonstrated result for efficacy | 1 trial | meta-analysis | | Trial | control | p<0.05 | harm | NS |
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SMILE, 1995 | zofenopril vs placebo | Long term death (1 year) 0.70 [0.54; 0.93] death or severe congestive heart failure 0.67 [0.49; 0.93] | | |
Trial | Treatments | Patients | Method |
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SMILE, 1995 | zofenopril initial dose 7.5 mg, up to a tagert dos eof 30mg twice daily (n=772) vs. placebo (n=784) | patients within 24 hours after a acute anterior myocardial infarction who were not undergoing thrombolysis | double blind Parallel groups Sample size: 772/784 Primary endpoint: death or severe congestive FU duration: 1 year |
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