| Trial | Treatments | Patients | Method |
|---|
| TOMIIS, 1994 | late PTCA (n=25) vs. no PTCA (n=19) | patients with a recent, first Q-wave myocardial infarction and an occluded infarct-related coronary artery | open Sample size: 25/19 Primary endpoint: Left ventricular ejection fraction FU duration: 4 months, fixed |
| Horie et al, 1998 | late revascularization by primary PTCA (n=44) vs. no PTCA (n=39) | patients with initial Q-wave anterior myocardial infarction >24 hours after onset | Sample size: 44/39 Primary endpoint: FU duration: 50 months, mean |
| TOAT, 2002 | late revascularization (late intervention and stent to the LAD + medical therapy) (n=32) vs. conservative therapy (medical therapy) (n=34) | symptom-free patients after acute myocardial infarction | open Sample size: 32/34 Primary endpoint: FU duration: 12 months, fixed |
| DECOPI, 2004 | percutaneous revascularization carried out 2-15 days after symptom onset (n=109) vs. medical treatment (n=103) | patients with a first Q-wave myocardial infarction and an occluded infarct vessel | open Sample size: 109/103 Primary endpoint: FU duration: 34 months, mean |
| Silva et al, 2005 | percutaneous coronary intervention (n=18) vs. conservative therapy (no-PCI) (n=18) | patients with occluded infarct-related artery between 12 h and 14 days post-anterior MI were | open Sample size: 18/18 Primary endpoint: FU duration: 6 months, fixed |
| OAT, 2006 | routine PCI and stenting (n=1082) vs. optimal medical therapy alone (n=1084) | stable patients who had total occlusion of the infarct-related artery 3 to 28 days after myocardial infarction and who met a high-risk criterion ( | open Sample size: 1082/1084 Primary endpoint: FU duration: 35 months, mean |
| TOSCA-2, 2006 | PCI with stenting (n=195) vs. optimal medical therapy alone (n=186) | patients with an occluded native infarct-related artery 3 to 28 days after MI | open Sample size: 195/186 Primary endpoint: IRA patency and change in LV ejection fraction FU duration: 12 months, fixed |
