fractional-flow-reserve-guided PCI

Description Results NMA

cardiovascular events 0.72 [0.54; 0.96]

Death from any cause 0.58 [0.26; 1.32]

Death from any cause 0.58 [0.26; 1.32]

Myocardial infarction 0.66 [0.42; 1.04]

Repeat vascularization 0.68 [0.45; 1.05]

cardiovascular death 0.51 [0.05; 5.48]

Myocardial infarction ∞ [NaN; ∞]

cardiovascular events 1.62 [0.78; 3.37]

Repeat vascularization 1.21 [0.38; 3.83]

FFR-guided PCI (PCI with implantation of drug-eluting stents guided by FFR measurements in addition to angiography (n=509)

vs.

angiography-PCI (PCI with implantation of drug-eluting stents guided by angiography alone) (n=496)

open

Parallel groups

Sample size: 509/496

Primary endpoint: death, MI, CABG surgery, or repeat PCI

FU duration: 1 year

PCI (n=90)

vs.

deferral (no PCI) (n=91)

open

Parallel groups

Sample size: 90/91

Primary endpoint:

FU duration: 24 months