agents to slow down human AAA-expansion | propanolol | versus placebo or control No demonstrated result for efficacy | 3 trials | meta-analysis | | Trial | control | p<0.05 | harm | NS |
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| vs placebo | | | | | vs placebo | | | | | vs control | | | |
Trial | Treatments | Patients | Method |
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Lindholt, 1999 | Propanolol 40 mg/bid (n=30) vs. Placebo (n=24) | | double blind Parallel groups Sample size: 30/24 Primary endpoint: FU duration: 24 mo | PATI, 2002 | Propanolol 20–240 mg/d (n=276) vs. Placebo (n=272) | | double blind Parallel groups Sample size: 276/272 Primary endpoint: FU duration: 30 mo | Wilmink, 2000 | Propanolol 40 mg/d (n=256) vs. control (n=221) | | open Parallel groups Sample size: 256/221 Primary endpoint: FU duration: 33 mo |
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