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Dipyridamol
antiplatelets drug
systematic review
meta-analysis
network meta-analysis
dipyridamol monoacetate - dipyridamole monoacetate
Select
acute coronary syndrome
CABG surgery
cardiovascular prevention
coronary artery disease
percutaneous coronary intervention
peripheral vascular diseases
post myocardial infarction
stable angina
thrombosis prevention
antiplatelet drugs
dipyridamol
platelet aggregation inhibitors
vs placebo or control
vs placebo or no treatment
vs aspirin
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Description
Synopsis
Comparison
Treatments
Patients
Characteristics
Method
Risk of bias
References
None
Tools
Indexation
Results
Global trial result
Main results
All results
All result tag
NCT results
Major bleeding (44)
Non fatal MI (35)
Non fatal stroke (32)
Non vascular death (29)
Cardiovascular death (27)
cardiovascular events (25)
Deep vein thrombosis (17)
fatal pulmonary embolism (17)
non-fatal pulmonary embolism (17)
non pulmonary embolism death (12)
Vascular death (8)
All cause death (7)
Vascular events (7)
Fatal MI (6)
Bleeding (6)
proximal DVT (5)
wound haematoma / infection (5)
stroke (fatal and non fatal) (4)
myocardial infarction (fatal and non fatal) (4)
Coronary event (3)
Adverse events (3)
Fatal stroke (3)
Amputation (3)
Non cerebral major bleeding (3)
Fatal bleeding (3)
refractory ischemia (1)
fatal bleeding (1)
Revascularization (1)
all cause death, MI, stroke (1)
ischemic stroke (1)
Options
Numeric
bar chart
forest plot
medians
Trial
Studied trt
Control trt
patients
tags
ROB
Trial result
Major bleeding
Non fatal MI
acute coronary syndrome
Prandoni, 1991
aspirin + dipyridamol
placebo
Low risk of bias
negative
-55%
CABG surgery
Pantely, 1979
aspirin + dipyridamol
control
negative
Des Moines, 1980
aspirin + dipyridamol
control
-
Brussels, 1987
aspirin + dipyridamol
control
negative
-48%
Czech, 1986
aspirin + dipyridamol
control
-
Toronto dipyridamole, 1987
dipyridamol
control
-
Mayo-A, 1984
aspirin + dipyridamol
placebo
Low risk of bias
negative
Wadsworth, 1985
aspirin + dipyridamol
placebo
Low risk of bias
negative
Brooks, 1985
aspirin + dipyridamol
placebo
Low risk of bias
negative
Thaulow, 1987
aspirin + dipyridamol
placebo
Low risk of bias
-
Basel, 1989
aspirin + dipyridamol
placebo
Low risk of bias
negative
-100%
Leeds-B, 1985
aspirin + dipyridamol
placebo
Low risk of bias
-
GESIC (aspirin+dipyridamol), 1990
aspirin + dipyridamol
placebo
Low risk of bias
negative
Ekestrom, 1990
dipyridamol
placebo
Low risk of bias
-
cardiovascular prevention
Wirecki, 1967
dipyridamol
control
Low risk of bias
negative
Becker, 1967
dipyridamol
control
Low risk of bias
negative
Atlanta (Sbar), 1967
dipyridamol
control
Low risk of bias
negative
-25%
Hess (2), 1985
aspirin + dipyridamol
placebo
Low risk of bias
-
Schoop (2), 1983
aspirin + dipyridamol
placebo
Low risk of bias
-
VA study, 1986
aspirin + dipyridamol
placebo
Low risk of bias
-
Neumann, 1964
dipyridamol
placebo
Low risk of bias
-
Zion, 1961
dipyridamol
placebo
Low risk of bias
-
Igloe, 1970
dipyridamol
placebo
Low risk of bias
-
Dewar, 1961
dipyridamol
placebo
Low risk of bias
-
Kinsella, 1962
dipyridamol
placebo
Low risk of bias
-
Leiberman, 1964
dipyridamol
placebo
Low risk of bias
-
Foulds, 1960
dipyridamol
placebo
Low risk of bias
-
PARIS-II, 1986
dipyridamol + aspirin
placebo
Low risk of bias
negative
PARIS, 1980
dipyridamol + aspirin
placebo
Low risk of bias
negative
PARIS, 1980
dipyridamol + aspirin
aspirin
Low risk of bias
negative
coronary artery disease
Atlanta (Sbar), 1967
dipyridamol
control
Low risk of bias
negative
-25%
Becker, 1967
dipyridamol
control
Low risk of bias
negative
Wirecki, 1967
dipyridamol
control
Low risk of bias
negative
Zion, 1961
dipyridamol
placebo
Low risk of bias
-
Igloe, 1970
dipyridamol
placebo
Low risk of bias
-
Kinsella, 1962
dipyridamol
placebo
Low risk of bias
-
Leiberman, 1964
dipyridamol
placebo
Low risk of bias
-
Dewar, 1961
dipyridamol
placebo
Low risk of bias
-
Neumann, 1964
dipyridamol
placebo
Low risk of bias
-
Foulds, 1960
dipyridamol
placebo
Low risk of bias
-
PARIS, 1980
dipyridamol + aspirin
placebo
Low risk of bias
negative
PARIS-II, 1986
dipyridamol + aspirin
placebo
Low risk of bias
negative
PARIS, 1980
dipyridamol + aspirin
aspirin
Low risk of bias
negative
percutaneous coronary intervention
Schwartz (Toronto), 1988
aspirin + dipyridamol
placebo
Low risk of bias
suggesting
-72%
Nye (Dunedin), 1990
aspirin + dipyridamol
placebo
negative
Mayo-PTCA, 1989
aspirin + dipyridamol
placebo
negative
54%
White (aspirin+dipiridamol), 1991
aspirin + dipyridamol
placebo
negative
45%
peripheral vascular diseases
Schoop (2), 1983
aspirin + dipyridamol
placebo
Low risk of bias
-
VA study, 1986
aspirin + dipyridamol
placebo
Low risk of bias
-
Hess (2), 1985
aspirin + dipyridamol
placebo
Low risk of bias
-
post myocardial infarction
PARIS-II, 1986
dipyridamol + aspirin
placebo
Low risk of bias
negative
PARIS, 1980
dipyridamol + aspirin
placebo
Low risk of bias
negative
PARIS, 1980
dipyridamol + aspirin
aspirin
Low risk of bias
negative
stable angina
Wirecki, 1967
dipyridamol
control
Low risk of bias
negative
Becker, 1967
dipyridamol
control
Low risk of bias
negative
Atlanta (Sbar), 1967
dipyridamol
control
Low risk of bias
negative
-25%
Igloe, 1970
dipyridamol
placebo
Low risk of bias
-
Zion, 1961
dipyridamol
placebo
Low risk of bias
-
Leiberman, 1964
dipyridamol
placebo
Low risk of bias
-
Dewar, 1961
dipyridamol
placebo
Low risk of bias
-
Neumann, 1964
dipyridamol
placebo
Low risk of bias
-
Kinsella, 1962
dipyridamol
placebo
Low risk of bias
-
Foulds, 1960
dipyridamol
placebo
Low risk of bias
-
thrombosis prevention
Chicago, 1982
aspirin + dipyridamol
control
Exploratory
negative
Australian I, 1975
dipyridamol + aspirin
control
Risk of bias
-
Zekert-III, 1977
dipyridamol + aspirin
control
Risk of bias
-
Parodi II, 1973
dipyridamol + aspirin
control
Risk of bias
-
Parodi I, 1973
dipyridamol + aspirin
control
Exploratory
suggesting
Weiss, 1977
dipyridamol + aspirin
control
Exploratory
-
Harjola DVT, 1982
dipyridamol + aspirin
control
Risk of bias
-
Toulouse I, 1979
dipyridamol + aspirin
control
Risk of bias
-
Australian II, 1976
dipyridamol + aspirin
control
Risk of bias
-
Lyon-I, 1975
aspirin + dipyridamol
no treatment
Exploratory
suggesting
Morris-B , 1977
aspirin + dipyridamol
no treatment
Exploratory
negative
Morris-A , 1977
dipyridamol
no treatment
Exploratory
negative
Hamburg, 1976
aspirin + dipyridamol
placebo
Exploratory
negative
Frankfurt, 1981
aspirin + dipyridamol
placebo
Low risk of bias
negative
Encke-II , 1976
aspirin + dipyridamol
placebo
Exploratory
negative
Encke IB, 1976
dipyridamol + aspirin
placebo
Low risk of bias
-
Encke IA, 1976
dipyridamol + aspirin
placebo
Low risk of bias
-
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