Lisinopril angiotensin-Converting Enzyme Inhibitors  

MK-521 - Prinivil - Zestril - Lysinopril - Lisinopril      

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Trial Studied trt Control trt patientstagsROB Trial resultAll cause deathhospitalisation for heart failure

acute myocardial infarction  

GISSI 3, 1994   lisinoprilplaceboRisk of bias -

atrial fibrillation  

GISSI-3 (AF ancillary study), 2003     lisinoprilplacebonegative
Van den Burg, 1995   lisinoprilplaceboLow risk of bias negative

diabetes type 2  

ALLHAT (lisi vs chlor, diabetic subgroup), 2002       lisinoprilchlorthalidoneLow risk of bias negative-1%

heart failure  

Zwehl, 1990   lisinoprilcontrolnegative
Giles, 1990   lisinoprilcontrolnegative
Rucinska-c (lisinopril), 1000   lisinoprilcontrolnegative
Gilbert, 1993   lisinoprilplaceboLow risk of bias negative
International Study Group (Lewis), 1989   lisinoprilplaceboLow risk of bias -
ATLAS, 1999   lisinoprillisinoprilLow risk of bias -

hypertension  

ALLHAT (ACEI vs amlodipine), 2002     lisinoprilamlodipineLow risk of bias suggesting 5%
ALLHAT (lisi vs chlor, diabetic subgroup), 2002       lisinoprilchlorthalidoneLow risk of bias negative-1%
ALLHAT (ACEI vs chlorthalidone), 2002     lisinoprildiureticsLow risk of bias negative 0%