Interferon alpha interferon BIS A EFFACER  

     

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Trial Studied trt Control trt patientstagsROB Trial resultdeath (overall survival) progression or death (progression free survival PFS)

melanoma  

EORTC18952 (Eggermont), 2005   ID IFN alpha-2b (I M)observationadjuvantnegative-16%-16%
Nordic IFN Trial, 2011     ID IFN alpha-2b (I M)observationadjuvantsuggesting-9%-23%
EORTC18991 (Eggermont), 2008   PEG IFN alpha-2b (I M)observationadjuvantsuggesting-4%-13%
EORTC18871/DKG 80-1 (Kleeberg), 2004   rIFN alpha-2bobservationadjuvantnegative-4%4%
EORTC18871/DKG 80-1 stage III   rIFN alpha-2bobservation - 61%