Dapagliflozin antidiabetic drugs
systematic review meta-analysis network meta-analysis
 

BMS-512148 - BMS512148 - BMS 512148 - forxiga - dapagliflozin      

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Trial Studied trt Control trt patientstagsROB Trial resultcardiovascular eventsCardiovascular death

diabetes type 2  

Yang, 2015      NCTdapagliflozin -
Nauck, 2011      NCTdapagliflozindlipizide add on metformin -
Ferrannini (MB102013), 2010        NCTdapagliflozinplaceboLow risk of bias -
Komoroski (MB102007), 2009      NCTdapagliflozinplaceboExploratory -
List (MB102008), 2009        NCTdapagliflozinplaceboExploratory -
KOhan      NCTdapagliflozinplaceboLow risk of bias -
Kohan      NCTdapagliflozinplacebo -
Kohan      NCTdapagliflozinplacebo -
DECLARE TIMI 58, 2018        NCTdapagliflozinplaceboLow risk of bias -
Kaku, 2014      NCTdapagliflozinplacebo -
Wilding (MB102009), 2009        NCTdapagliflozinplacebo (add on insulin)Low risk of bias -
Wilding, 2012              NCTdapagliflozinplacebo (add on insulin) -
Mathieu, 2015      NCTdapagliflozinplacebo (add on MET + SAXA) -
Bailey (MB102014), 2010          NCTdapagliflozinplacebo (add on MET)Low risk of bias -
Bolinder, 2012          NCTdapagliflozinplacebo (add on MET) -
Schumm-Draeger , 2015      NCTdapagliflozinplacebo (add on MET) -
Matthaei, 2015      NCTdapagliflozinplacebo (add on MET+SU) -
Rosenstock, 2012        NCTdapagliflozinplacebo (add on TZD) -
MB102035    NCTdapagliflozinplacebo (on top standard treatment) -
Cefalu, 2015        NCTdapagliflozinplacebo (on top standard treatment) -
Leiter, 2016      NCTdapagliflozinplacebo (on top standard treatment) -
MB102073    NCTdapagliflozinplacebo (on top standard treatment) -
Weber      NCTdapagliflozinplacebo (on top standard treatment) -
MB102061    NCTdapagliflozinplacebo add on DPP-4 -
Rosenstock, 2015      NCTdapagliflozinSaxagliptin (add on MET) -
Kohan      NCTdapagliflozin + merformindapagliflozin -
Strojek, 2011          NCTdapagliflozin + Glimepirideglimepiride -
MB102034, 2016      NCTdapagliflozin + merforminmetformin or dapa -



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