Carvedilol beta-blockers  

BM-14190  - BM 14190  - Eucardic - Coropres - Kredex  - Dilatrend  - Coreg  - Querto  - carvedilol       

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Trial Studied trt Control trt patientstagsROB Trial resultAll cause deathCardiovascular death

acute myocardial infarction  

Basu , 1997     Carvedilol placeboLow risk of bias suggesting-37%

heart failure  

ANZ-HeFT, 1997         carvedilolplaceboLow risk of bias negative-23%-10%
COPERNICUS, 2002     carvedilolplaceboLow risk of bias suggesting-33%
CAPRICORN, 2001   carvedilolplaceboLow risk of bias suggesting-22%-24%
Metra, 1994   carvedilolplacebo -
Olsen, 1995     carvedilolplacebo -
Krum, 1995     carvedilolplacebo -
Bristow (MOCHA), 1996     carvedilolplaceboLow risk of bias -
Parker, 1996       carvedilolplaceboLow risk of bias negative-30%
Colucci, 1996     carvedilolplaceboLow risk of bias -
Cohn, 1997     carvedilolplacebo -
Carvedilol U.S. Trials (elderly subgroup), 1996     Carvedilolplacebosuggesting-55%
COPERNICUS (elderly subgroup), 2001     Carvedilolplacebosuggesting-25%
CARMEN (carvedilol alone), 2004   carvedilolenalaprilnegative-1%-8%
COMET, 2003   carvedilolmetoprololLow risk of bias suggesting-14%-18%

hypertension  

Cice et al, 2003     carvedilolplacebosuggesting-57%
Nakao et al, 2007   carvedilolplacebo -