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Vitamin e
antioxydants
systematic review
meta-analysis
network meta-analysis
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cardiovascular prevention
peripheral vascular diseases
antioxydant
vitamine E
vs placebo or control
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Description
Synopsis
Comparison
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Characteristics
Method
Risk of bias
References
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Results
Global trial result
Main results
All results
All result tag
NCT results
All cause death (27)
stroke (fatal and non fatal) (27)
Cardiovascular death (17)
Non fatal MI (17)
Non fatal stroke (17)
cardiovascular events (17)
ischemic stroke (17)
Haemmorhagic stroke (17)
Coronary event (17)
Coronary death (17)
Amputations (5)
Amputation (5)
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medians
Trial
Studied trt
Control trt
patients
tags
ROB
Trial result
All cause death
stroke (fatal and non fatal)
cardiovascular prevention
GISSI, 1999
vitamin E
control
Risk of bias
negative
-8%
-13%
PPP, 2001
vitamin E
control
Risk of bias
negative
7%
24%
ATBC vitamin E, 1994
vitamin E
placebo
Low risk of bias
suggesting
-7%
CHAOS, 1996
vitamin E
placebo
Low risk of bias
suggesting
29%
HOPE, 2000
vitamin E
placebo
Low risk of bias
negative
17%
AREDS, 2001
vitamin E
placebo
Low risk of bias
negative
5%
SPACE, 2000
vitamin E
placebo
Low risk of bias
suggesting
9%
-15%
Linxian, 1993
vitamin E
placebo
negative
WACS vitamin E, 2007
NCT
vitamin E
placebo
Low risk of bias
negative
2%
-15%
PHS II vitamin E, 2008
NCT
vitamin E
placebo
Low risk of bias
negative
3%
5%
WHS vitamin E, 2005
NCT
vitamin E
placebo
Low risk of bias
negative
-2%
HOPE renal insufficiency subgroup, 2004
vitamin E
placebo
Low risk of bias
negative
-10%
3%
ASAP, 2000
vitamin E
placebo
Low risk of bias
negative
100%
ATBC 2nd prev subgroup (vitamin E), 1998
vitamin E
placebo
Low risk of bias
negative
peripheral vascular diseases
Livingstone, 1958
placebo
-
Hamilton, 1953
placebo
-
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