CEPT inhibition

systematic review meta-analysis network meta-analysis

Select cardiovascular prevention All type of patient       CETP inhibitor anacetrapibtorcetrapib vs placebo      

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Group by Group by... nothing pathology treatment patient comparator classe classe comparator mechanism clinical condition MA  in first nothing pathology treatment patient comparator classe classe comparator mechanism clinical condition  in second nothing pathology treatment patient comparator classe classe comparator mechanism clinical condition  in third	Description Synopsis Comparison Treatments Patients Characteristics Method Risk of bias References None Tools Indexation					Results Global trial result Main results All results All result tag NCT results	All cause death (6)Cardiovascular death (4)Coronary revascularization (4)cardiovascular events (4)stroke (fatal and non fatal) (4)Non fatal MI (4)Coronary event (3)cardiovascular events including revascularization (3)Coronary death (3)Non fatal stroke (2) Options Numeric bar chart forest plot medians
Trial	Studied trt	Control trt	patients	tags	ROB	Trial result	All cause death	Cardiovascular death
cardiovascular prevention
anacetrapib
DEFINE, 2010    NCT	anacetrapib	placebo			Exploratory	negative
REALIZE, 2015      NCT	anacetrapib	placebo			Low risk of bias	negative
torcetrapib
RADIANCE 1, 2007      NCT	torcetrapib	placebo			Exploratory	negative
ILLUMINATE, 2007      NCT	torcetrapib	placebo			Low risk of bias	negative
RADIANCE 2, 2007	torcetrapib	placebo			Low risk of bias	-
ILLUSTRATE, 2007      NCT	torcetrapib	placebo			Exploratory	negative