Enalapril angiotensin-Converting Enzyme Inhibitors  

     

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Trial Studied trt Control trt patientstagsROB Trial resultAll cause deathhospitalisation for heart failure

acute myocardial infarction  

CONSENSUS 2, 1992   enalaprilplaceboLow risk of bias -
Schulman, 1995     enalaprilplaceboLow risk of bias -

atrial fibrillation  

Ueng, 2003     enalaprilcontrolsuggesting
SOLVD (AF ancillary study), 2003     enalaprilplacebosuggesting

heart failure  

Rucinska-b (enalapril), 1991   enalaprilcontrolnegative
Enalapril CHF investigators, 1987   enalaprilcontrolnegative
Rucinska-a (enalapril), 1991   enalaprilcontrolnegative
SOLVD treatment, 1991    NCTenalaprilplaceboLow risk of bias suggesting -11%-29%
SOLVD prevention, 1992    NCTenalaprilplaceboLow risk of bias -
Cleland, 1985   enalaprilplaceboLow risk of bias negative
CONSENSUS, 1987   enalaprilplaceboLow risk of bias negative
Dickstein, 1991   enalaprilplaceboLow risk of bias negative
Sharpe, 1984   enalaprilplaceboLow risk of bias -
McGrath, 1985     enalaprilplaceboLow risk of bias -
Chrysant, 1985   enalaprilplaceboLow risk of bias -
CASSIS (enalapril), 1995   enalaprilplaceboLow risk of bias -
NETWORK (2.5 bid vs 10 bid), 1998   enalaprilenalaprilLow risk of bias -
NETWORK (5 bid vs 10 bid), 1998   enalaprilenalaprilLow risk of bias -
V-HeFT II, 1991   enalaprilhydralazine+ISDNLow risk of bias -

hypertension  

ANBP2, 2003     enalaprildiureticsRisk of bias negative-7%
ABCD (H), 1998     enalaprilnisoldipineLow risk of bias suggesting-22%

patients at high risk for cardiovascular events  

CAMELOT (enalapril), 2004     enalaprilplaceboLow risk of bias negative30%