Aminoglutethimide aromatase inhibitors
systematic review meta-analysis network meta-analysis
 

Orimeten - Cytadren - Aminoglutethimide      

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Trial Studied trt Control trt patientstagsROB Trial resulthot flushes nausea

advanced breast cancer (metastatic)  

Mercer, 1993   aminoglutethimidehydrocortisonenegative
Canney, 1988   aminoglutethimidemedroxyprogesterone acetatesuggesting-77%
Garcia-Giralt, 1992   aminoglutethimidemedroxyprogesterone acetatenegative
Samonis, 1994   aminoglutethimidemedroxyprogesterone acetatenegative∞%
Lundgren, 1989   aminoglutethimidemegestrol acetatenegative
Russell, 1997   aminoglutethimidemegestrol acetatenegative
Alonso-Munoz, 1988   aminoglutethimidetamoxifennegative
Gale, 1994   aminoglutethimidetamoxifennegative
Ingle, 1986   aminoglutethimide + tamoxifentamoxifennegative -4%116%
Powles, 1984   combination of hormone therapiestamoxifennegative 170%



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