nontaxane microtubule dynamics inhibitor

Eribulin      

Select            
Trial Studied trt Control trt patientstagsROB Trial resultdeath (overall survival) progression or death (progression free survival PFS)

advanced breast cancer (metastatic)  

eribulin  
Trial 301 (Kaufman), 2015        NCTeribulincapecitabineRisk of bias negative-12%8%
Vahdat, 2013      NCTeribulinixabepiloneExploratory -
EMBRACE (Cortes), 2011        NCTeribulintreatment of physicianRisk of bias conclusive-19%-13%