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selective estrogen receptor modulator (SERM)
systematic review
meta-analysis
network meta-analysis
Tamoxifen
-
Toremifene
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advanced breast cancer (metastatic)
All type of patient
Selective estrogen receptor modulators (SERMs)
tamoxifen
toremifene
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advanced breast cancer (metastatic)
tamoxifen
Viladiu, 1985
-
Kuss, 1997
tamoxifen
-
De Lena, 1990
tamoxifen
-
Takatsuka, 1989
tamoxifen 20 mg/day
40 mg/day
-
Ingle, 1986
tamoxifen
bilateral oophorectomy
-
Perry, 1985
tamoxifen + CAT
CAT
-
Mouridsen, 1985
tamoxifen + CMF
CMF
-
Spooner, 1991
loading dose regimen of tamoxifen
conventional dosing
-
Gockerman, 1986
tamoxifen
diethylstilbestrol
-
Beex, 2006
intermittent tamoxifen
Intermittent tamoxifen
-
Muss, 1994
tamoxifen
medroxyprogesterone
-
Castiglione-Gertsch, 1993
tamoxifen
medroxyprogesterone acetate
-
van, 1986
tamoxifen
medroxyprogesterone acetate
-
Stuart, 1996
tamoxifen
megestrol acetate
-
Gill, 1993
tamoxifen
megestrol acetate
-
Ettinger, 1986
tamoxifen
megestrol acetate
-
Kellokumpu-Lehtinen, 1987
tamoxifen
nandrolone decanoate
-
Beelen, 2014
tamoxifen
no systemic treatment
-
Sawka, 1997
tamoxifen
ovarian ablation
-
Willsher, 1996
tamoxifen
radiotherapy
-
Mauriac, 1986
alternating
successive
-
Buchanan, 1986
tamoxifen
surgical oophorectomy
-
toremifene
Nomura, 1993
toremifene
tamoxifen
Low risk of bias
negative
Gershanovich, 1997
toremifene
tamoxifen
negative
Milla-Santos, 2001
toremifene
tamoxifen
Low risk of bias
negative
Hayes, 1995
toremifene
tamoxifen
negative
Stenbygaard, 1993
toremifene
tamoxifen
negative
Pyrhonen, 1997
toremifene
tamoxifen
suggesting
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