endothelin receptor antagonist

systematic review meta-analysis network meta-analysis

Select acute heart failure All type of patient       endothelin receptor antagonisthuman B-type natriuretic peptide nesiritide vs placebo or controlvs active treatment      

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Group by Group by... nothing pathology treatment patient comparator classe classe comparator mechanism clinical condition MA  in first nothing pathology treatment patient comparator classe classe comparator mechanism clinical condition  in second nothing pathology treatment patient comparator classe classe comparator mechanism clinical condition  in third	Description Synopsis Comparison Treatments Patients Characteristics Method Risk of bias References None Tools Indexation					Results Global trial result Main results All results All result tag NCT results	All cause death (4)Death from any cause or hospitalization for heart failure (1)amelioration of Dyspnea at 24 h (1)30-day death (1)hospitalisation for heart failure (1) Options Numeric bar chart forest plot medians
Trial	Studied trt	Control trt	patients	tags	ROB	Trial result	All cause death	Death from any cause or hospitalization for heart failure
acute heart failure
nesiritide
NSGET (comparative trial), 2000	nesiritide	control			Low risk of bias	remark
NSGET (efficacy trial), 2000	nesiritide	placebo			Low risk of bias	negative
PROACTION, 2003	nesiritide	placebo			Low risk of bias	negative
BNP-CARDS, 2007          NCT	nesiritide	placebo			Low risk of bias	remark
FUSION 2, 2008        NCT	nesiritide	placebo			Low risk of bias	remark
ASCEND-HF, 2011        NCT	nesiritide	placebo			Low risk of bias	negative
VMAC (intravenous neseritide), 2002      NCT	nesiritide	placebo			Low risk of bias	remark
PRECEDENT, 2002      NCT	nesiritide	dobutamine			Exploratory	remark
VMAC (24h), 2002      NCT	nesiritide	nitroglycerin			Risk of bias	negative
FUSION 1, 2004    NCT	nesiritide	standard care			Low risk of bias	remark